Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   I6G43_RS02225 Genome accession   NZ_CP065706
Coordinates   455279..457246 (+) Length   655 a.a.
NCBI ID   WP_038806417.1    Uniprot ID   A0A7T2ZP43
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 450279..462246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS02210 (I6G43_02210) - 450698..451729 (+) 1032 WP_038806418.1 sensor histidine kinase -
  I6G43_RS02215 (I6G43_02215) - 451862..453346 (-) 1485 WP_000743606.1 DUF1846 domain-containing protein -
  I6G43_RS02220 (I6G43_02220) - 453499..455109 (+) 1611 WP_001156778.1 glycoside hydrolase family 13 protein -
  I6G43_RS02225 (I6G43_02225) amiA 455279..457246 (+) 1968 WP_038806417.1 peptide ABC transporter substrate-binding protein Regulator
  I6G43_RS02230 (I6G43_02230) amiA3 457396..459357 (+) 1962 WP_197905371.1 peptide ABC transporter substrate-binding protein Regulator
  I6G43_RS02235 (I6G43_02235) - 459547..460992 (+) 1446 WP_038806415.1 LCP family protein -
  I6G43_RS02240 (I6G43_02240) cps4B 460994..461725 (+) 732 WP_038806414.1 capsular polysaccharide biosynthesis protein Cps4B -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 72398.05 Da        Isoelectric Point: 5.2154

>NTDB_id=513205 I6G43_RS02225 WP_038806417.1 455279..457246(+) (amiA) [Streptococcus oralis strain FDAARGOS_886]
MKSKKWLLGAGAVLSAALLLTACGQSEKKADAPKTFSYVYAIDPSSLDYSVTSKSSTSDVIANVVDGLLENDKYGNLIPS
LAEDWSVSKDGLTYTYKLRKGVKWYTSEGEEYAEVKAQDFVTGLKHAADGKSDGLSLLQDSIKGLAAYISGESNDFSTVG
VKAVDDYTVEYTLNKPESFWNSKVTTATMLPVNEEFLNSKGSDYGAPTPSSILYNGPYFLKSLTSKSVIEYEKNPNYWDK
DNVKIDNIKLTFYDGSDQESLIRSFTQGAYTTARLFPTSSNFESTKKEYGDKIVYSPQEATSYYLTVNVNRQSYNKTAKT
DEAQKTSTKEALLNKNFRQALNFALDRHSYTAQLNGEEGADKIIRNSLVPHDYVQVGEKTFGELAQAELVSYGDQWKDVA
LTDGKDTLYSPEKAKAAFAKAKAELQAKGVTFPIRLDVPVEQTDVIAVQQTNSLKQSIESTLGTENVIVDVLQMTDNEKM
SITSQAKVPSQKDYDLNGTGWGPDYQDPATYLNILDAKKGSALKHLGITRGKDPEVMAQVGLDEYKKLLDDAAAETSDLN
KRYEKYAKAQAWVSDSSLLIPVASSGGSPTVSRTVPFSKAYSQVGIKGDPFVFKGLELQKDVVTTKEYEEALKKWQKEKI
ETNAKYQKELEKHVK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=513205 I6G43_RS02225 WP_038806417.1 455279..457246(+) (amiA) [Streptococcus oralis strain FDAARGOS_886]
ATGAAATCGAAAAAGTGGCTCTTAGGAGCAGGTGCTGTTTTGAGTGCAGCCCTACTGTTAACTGCTTGTGGGCAAAGTGA
AAAGAAGGCTGATGCTCCCAAGACATTTTCTTATGTCTATGCAATAGATCCATCATCTTTGGACTACAGCGTGACGAGCA
AGAGCTCAACTTCTGACGTTATAGCCAACGTTGTCGATGGCCTCTTGGAAAACGATAAATACGGGAACTTGATTCCGTCG
CTTGCAGAAGATTGGTCTGTTTCTAAAGATGGCTTGACCTATACCTACAAACTTCGTAAGGGTGTAAAATGGTATACTTC
TGAGGGAGAAGAGTATGCTGAAGTCAAGGCTCAGGACTTTGTTACGGGTCTGAAACATGCAGCTGATGGTAAATCAGACG
GCCTCTCTCTCCTTCAAGATTCTATCAAAGGTTTGGCTGCCTACATTAGTGGTGAAAGCAATGACTTTTCTACTGTAGGA
GTCAAGGCTGTTGACGATTATACGGTTGAATATACACTCAATAAACCAGAAAGTTTCTGGAACTCTAAAGTCACAACTGC
AACCATGCTTCCAGTTAATGAAGAATTCTTGAATTCTAAAGGGAGTGACTATGGTGCACCAACACCATCAAGTATTCTTT
ATAACGGTCCTTATTTCTTGAAATCATTGACTTCAAAATCAGTCATCGAATATGAAAAGAATCCAAACTACTGGGATAAG
GACAATGTTAAGATTGACAACATCAAACTAACTTTCTACGATGGATCTGACCAAGAATCTTTGATTCGCAGCTTTACACA
AGGTGCTTATACAACAGCCCGTCTCTTCCCAACAAGCTCAAACTTTGAGTCAACTAAGAAAGAGTACGGCGATAAGATTG
TCTACAGTCCACAAGAAGCGACAAGCTACTACCTCACTGTTAACGTAAACCGCCAGTCTTACAATAAAACAGCCAAAACA
GACGAAGCTCAAAAAACATCAACCAAAGAAGCTCTTCTCAACAAGAACTTCCGTCAGGCACTGAACTTTGCCCTTGACCG
TCACTCTTACACGGCTCAGTTGAATGGTGAAGAAGGGGCGGACAAGATTATCCGTAATAGCCTAGTACCTCATGACTACG
TTCAAGTAGGTGAAAAGACATTTGGAGAGTTGGCTCAGGCAGAGCTCGTTTCTTATGGTGACCAGTGGAAAGATGTAGCC
CTTACAGATGGCAAGGATACGCTATACAGTCCTGAAAAAGCCAAGGCAGCCTTTGCAAAGGCTAAGGCAGAATTGCAGGC
CAAGGGTGTCACCTTCCCAATCCGTTTGGATGTTCCAGTTGAACAGACCGATGTCATTGCCGTTCAACAAACCAACTCAC
TCAAGCAGTCTATCGAGTCAACACTTGGTACAGAGAATGTCATTGTTGATGTCCTTCAAATGACAGATAATGAAAAAATG
AGTATTACGTCCCAAGCCAAAGTGCCATCCCAAAAAGATTATGACTTGAATGGAACTGGTTGGGGGCCAGACTATCAGGA
CCCAGCTACCTACCTCAACATTCTTGATGCTAAGAAGGGTTCTGCTCTTAAACACTTGGGGATCACTCGCGGAAAAGATC
CAGAAGTGATGGCTCAGGTCGGTCTAGACGAATACAAGAAACTCTTGGATGATGCCGCAGCTGAAACCAGCGACCTCAAT
AAGCGTTATGAGAAATACGCTAAAGCTCAAGCTTGGGTATCGGATAGTTCGCTCTTAATCCCAGTTGCTTCTTCAGGTGG
TTCTCCAACTGTTAGTCGAACTGTACCATTCTCAAAAGCATACTCTCAAGTCGGAATCAAGGGAGACCCGTTTGTATTCA
AAGGTTTGGAGCTGCAAAAGGATGTCGTGACTACAAAAGAATACGAAGAAGCTCTCAAGAAATGGCAGAAAGAAAAGATT
GAAACAAATGCCAAATACCAAAAAGAGCTAGAAAAACACGTCAAATAG

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(77-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZP43

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

55.167

100

0.554
  amiA3 Streptococcus thermophilus LMD-9

54.325

100

0.547
  amiA3 Streptococcus thermophilus LMG 18311

53.869

100

0.542