Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I6H03_RS08985 Genome accession   NZ_CP065607
Coordinates   1738404..1739528 (-) Length   374 a.a.
NCBI ID   WP_000228547.1    Uniprot ID   -
Organism   Escherichia coli strain FDAARGOS_946     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1733404..1744528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H03_RS08955 (I6H03_08960) yrdA 1735204..1735758 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  I6H03_RS08960 (I6H03_08965) yrdB 1735734..1735991 (-) 258 WP_001070590.1 DUF1488 domain-containing protein -
  I6H03_RS08965 (I6H03_08970) aroE 1735988..1736806 (-) 819 WP_000451254.1 shikimate dehydrogenase -
  I6H03_RS08970 (I6H03_08975) tsaC 1736811..1737383 (-) 573 WP_001301437.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  I6H03_RS08975 (I6H03_08980) yrdD 1737388..1737930 (-) 543 WP_001129722.1 type I DNA topoisomerase -
  I6H03_RS08980 (I6H03_08985) smg 1737959..1738432 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  I6H03_RS08985 (I6H03_08990) dprA 1738404..1739528 (-) 1125 WP_000228547.1 DNA-protecting protein DprA Machinery gene
  I6H03_RS08990 (I6H03_08995) def 1739658..1740167 (+) 510 WP_000114985.1 peptide deformylase -
  I6H03_RS08995 (I6H03_09000) fmt 1740182..1741129 (+) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  I6H03_RS09000 (I6H03_09005) rsmB 1741175..1742464 (+) 1290 WP_001359006.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H03_RS09005 (I6H03_09010) trkA 1742486..1743862 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  I6H03_RS09010 (I6H03_09015) mscL 1743992..1744402 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40967.87 Da        Isoelectric Point: 6.2655

>NTDB_id=512206 I6H03_RS08985 WP_000228547.1 1738404..1739528(-) (dprA) [Escherichia coli strain FDAARGOS_946]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQSNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGATITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=512206 I6H03_RS08985 WP_000228547.1 1738404..1739528(-) (dprA) [Escherichia coli strain FDAARGOS_946]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAATCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGCGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

49.051

98.663

0.484
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393