Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   I6H05_RS09590 Genome accession   NZ_CP065604
Coordinates   1972299..1973708 (-) Length   469 a.a.
NCBI ID   WP_005566816.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain FDAARGOS_948     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1967299..1978708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H05_RS09570 (I6H05_09570) ssb 1969004..1969483 (+) 480 WP_005544986.1 single-stranded DNA-binding protein Machinery gene
  I6H05_RS09575 (I6H05_09575) - 1969589..1970443 (-) 855 WP_005544984.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  I6H05_RS09580 (I6H05_09580) aroB 1970446..1971534 (-) 1089 WP_005544982.1 3-dehydroquinate synthase -
  I6H05_RS09585 (I6H05_09585) aroK 1971558..1972085 (-) 528 WP_005555432.1 shikimate kinase AroK -
  I6H05_RS09590 (I6H05_09590) comE 1972299..1973708 (-) 1410 WP_005566816.1 type IV pilus secretin PilQ Machinery gene
  I6H05_RS09595 (I6H05_09595) - 1973728..1974120 (-) 393 WP_005544975.1 hypothetical protein -
  I6H05_RS09600 (I6H05_09600) - 1974120..1974644 (-) 525 WP_005543969.1 hypothetical protein -
  I6H05_RS09605 (I6H05_09605) - 1974641..1975159 (-) 519 WP_025298239.1 PilN domain-containing protein -
  I6H05_RS09610 (I6H05_09610) - 1975170..1975979 (-) 810 WP_005544971.1 hypothetical protein -
  I6H05_RS09615 (I6H05_09615) - 1976113..1978680 (+) 2568 WP_005566815.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 469 a.a.        Molecular weight: 51734.42 Da        Isoelectric Point: 7.4773

>NTDB_id=512190 I6H05_RS09590 WP_005566816.1 1972299..1973708(-) (comE) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
MKSILSRRLKCGLFFGCFLSLAVQAEQNPVFSIRLKQAPLVPTLQQLALAHNTNLIIDDELQGTVSLQLENVDLDQLFRS
VAKIKQLDLWQENGIYYFTKGDTNTKFAGKMEEPFPLSLPMAEEPAQLNTATIKLHFAKASEVMKSLTGGSGSLLSPNGS
ITFDDRSNLLLIQDEPRSVRNIKKLIKELDKPIEQIAIEARIVTINDESLKELGVRWGIFSPTDNAHRIGGSLAGNGFDN
LVNQLNVNFPTTTTPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYILVNEKSGSQ
SVEFREAVLGLEVTPHISQDKQILLDLIVSQNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGETPDAFKQKRIGVNEQIMAKGENKKDLNRK

Nucleotide


Download         Length: 1410 bp        

>NTDB_id=512190 I6H05_RS09590 WP_005566816.1 1972299..1973708(-) (comE) [Aggregatibacter actinomycetemcomitans strain FDAARGOS_948]
ATGAAATCGATCCTTTCCCGACGACTAAAGTGCGGTCTGTTTTTCGGGTGTTTTTTAAGTCTTGCGGTGCAGGCGGAACA
AAATCCGGTGTTTTCCATTCGGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCCCACAATACCA
ATTTGATTATTGACGATGAACTGCAAGGCACGGTGTCGTTACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCT
GTGGCAAAAATTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAAGGCGACACCAACACGAAATT
TGCCGGCAAAATGGAAGAGCCTTTCCCTCTTTCTCTGCCCATGGCGGAAGAACCGGCACAGCTGAACACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGGAGTGGTTCCCTGTTGTCGCCTAACGGCAGT
ATCACTTTCGACGATCGTAGCAATTTGTTGCTGATTCAGGATGAACCGCGCTCCGTCCGCAACATAAAAAAGCTGATTAA
GGAACTGGATAAACCCATTGAGCAAATCGCCATTGAAGCGCGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGG
GCGTGCGCTGGGGCATTTTCAGCCCGACGGACAACGCCCATCGTATCGGTGGCAGTTTGGCGGGCAACGGCTTTGATAAC
CTTGTCAATCAGTTAAACGTAAATTTTCCCACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGCGAAAATCAA
CGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTGGAAATCATCGCAAGCCCACGCCTGCTAA
CGACAAACAAAAAAAGCGCCAGCATCAAACAGGGGACGGAATTGCCCTATATTCTGGTGAACGAAAAAAGCGGTTCGCAA
AGCGTGGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCACGCCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCT
TATCGTCAGCCAAAACTCGCCGGGCAGCCGTGTGGCGTACGGTTTGGGCGAAGTGGTTTCTATTGATAAACAGGAGATTA
ATACACAAGTCTTCGCCAAGGACGGCGAAACCATTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAAGGAAAGTGAACGCCATCAAAAACGCGAGCT
GGTGATTTTTGTCACACCACATATTTTGCGTAAAGGCGAAACCCCGGACGCTTTCAAACAAAAGCGAATCGGGGTAAATG
AGCAAATCATGGCAAAAGGGGAGAATAAAAAGGACCTAAATAGGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(277-437)

Bacterial type II/III secretion system short domain (Secretin_N)

(130-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

71.812

95.309

0.684
  comE Haemophilus influenzae 86-028NP

70.917

95.309

0.676
  comE Glaesserella parasuis strain SC1401

52.86

93.177

0.493
  pilQ Vibrio campbellii strain DS40M4

41.244

92.537

0.382
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.822

91.258

0.382
  pilQ Vibrio cholerae strain A1552

41.822

91.258

0.382