Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SIR_RS18995 Genome accession   NC_022246
Coordinates   1897061..1897501 (+) Length   146 a.a.
NCBI ID   WP_041787618.1    Uniprot ID   -
Organism   Streptococcus intermedius B196     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892061..1902501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18970 (SIR_1807) - 1892311..1892865 (-) 555 WP_021003317.1 DNA-3-methyladenine glycosylase I -
  SIR_RS18975 (SIR_1808) ruvA 1892876..1893466 (-) 591 WP_021003318.1 Holliday junction branch migration protein RuvA Machinery gene
  SIR_RS18980 (SIR_1809) - 1893728..1894234 (+) 507 WP_021003319.1 helix-turn-helix domain-containing protein -
  SIR_RS18985 (SIR_1810) - 1894218..1894727 (+) 510 WP_041787616.1 RDD family protein -
  SIR_RS18990 (SIR_1811) hexB 1894873..1896819 (-) 1947 WP_021003321.1 DNA mismatch repair endonuclease MutL Machinery gene
  SIR_RS18995 (SIR_1812) brsR 1897061..1897501 (+) 441 WP_041787618.1 LytTR family DNA-binding domain-containing protein Regulator
  SIR_RS19000 (SIR_1813) - 1897498..1897956 (+) 459 WP_021003323.1 DUF3021 domain-containing protein -
  SIR_RS19005 (SIR_1814) hexA 1898097..1900655 (-) 2559 WP_021003324.1 DNA mismatch repair protein MutS Machinery gene
  SIR_RS19010 (SIR_1815) argR 1900818..1901258 (-) 441 WP_003075336.1 arginine repressor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 16969.71 Da        Isoelectric Point: 7.3973

>NTDB_id=51167 SIR_RS18995 WP_041787618.1 1897061..1897501(+) (brsR) [Streptococcus intermedius B196]
MKVQMHIDEKFSEERIIIEAPVLSDSVQQLLTFAQHIGKNKTIRAKKEEEIYLLNSTEIQRVYTENRQVWAETATDTYLL
GLPLYQVLELLPTDFLQISQSEIINIKHIDHLKLTGSGLIQIAMKNGQITYSSRRYLKVIKEKLQL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=51167 SIR_RS18995 WP_041787618.1 1897061..1897501(+) (brsR) [Streptococcus intermedius B196]
ATGAAAGTTCAAATGCATATTGACGAAAAATTTTCAGAAGAAAGGATCATTATTGAAGCGCCTGTTTTGTCGGATTCCGT
TCAACAACTACTAACATTTGCTCAACATATTGGTAAAAATAAAACCATTCGAGCAAAAAAAGAGGAGGAAATTTACCTAC
TAAATAGCACAGAGATACAACGCGTCTATACTGAAAATCGGCAAGTTTGGGCCGAAACAGCAACAGACACTTATCTCTTA
GGGCTTCCACTTTATCAAGTTTTGGAATTGCTTCCCACTGATTTTCTACAGATTTCCCAATCTGAAATCATTAACATCAA
ACATATCGATCATCTGAAATTGACTGGTAGTGGTCTGATTCAGATTGCAATGAAAAACGGTCAGATAACTTATTCATCTC
GCCGTTATCTCAAAGTCATAAAGGAGAAATTACAGCTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.986

100

0.37

Multiple sequence alignment