Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   STCNRZ1202_RS01455 Genome accession   NZ_CP065506
Coordinates   263641..264540 (+) Length   299 a.a.
NCBI ID   WP_014607953.1    Uniprot ID   A0AAN1ZWJ0
Organism   Streptococcus thermophilus strain CNRZ1202     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 258641..269540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1202_RS01435 (STCNRZ1202_01450) trkA 259778..261127 (-) 1350 WP_014607951.1 Trk system potassium transporter TrkA -
  STCNRZ1202_RS01440 (STCNRZ1202_01455) - 261415..261924 (+) 510 WP_011680717.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  STCNRZ1202_RS01445 (STCNRZ1202_01460) - 262236..262793 (+) 558 WP_002949523.1 ECF transporter S component -
  STCNRZ1202_RS01450 (STCNRZ1202_01465) - 262796..263446 (+) 651 WP_180476745.1 phosphatase PAP2 family protein -
  STCNRZ1202_RS01455 (STCNRZ1202_01470) comR 263641..264540 (+) 900 WP_014607953.1 helix-turn-helix domain-containing protein Regulator
  STCNRZ1202_RS01460 - 264778..265209 (+) 432 Protein_234 cysteine peptidase family C39 domain-containing protein -
  STCNRZ1202_RS01465 - 265239..265868 (+) 630 Protein_235 ABC transporter transmembrane domain-containing protein -
  STCNRZ1202_RS01470 comA 265977..266186 (+) 210 WP_270999752.1 peptidase Regulator
  STCNRZ1202_RS01475 (STCNRZ1202_01495) - 266241..266809 (+) 569 Protein_237 ATP-binding cassette domain-containing protein -
  STCNRZ1202_RS01480 (STCNRZ1202_01500) - 266917..267201 (+) 285 WP_347229667.1 DUF805 domain-containing protein -
  STCNRZ1202_RS01485 - 267452..267799 (-) 348 WP_232089310.1 DUF4173 domain-containing protein -
  STCNRZ1202_RS01490 - 267724..268620 (-) 897 WP_224103642.1 urease cluster protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35289.70 Da        Isoelectric Point: 5.0061

>NTDB_id=511360 STCNRZ1202_RS01455 WP_014607953.1 263641..264540(+) (comR) [Streptococcus thermophilus strain CNRZ1202]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=511360 STCNRZ1202_RS01455 WP_014607953.1 263641..264540(+) (comR) [Streptococcus thermophilus strain CNRZ1202]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

99.666

100

0.997
  comR Streptococcus thermophilus LMD-9

98.997

100

0.99
  comR Streptococcus salivarius strain HSISS4

94.983

100

0.95
  comR Streptococcus salivarius SK126

94.314

100

0.943
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.806

100

0.418