Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   STT55_RS05590 Genome accession   NZ_CP065502
Coordinates   1061629..1062969 (-) Length   446 a.a.
NCBI ID   WP_232979188.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST55     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1056629..1067969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT55_RS05560 (STT55_05520) - 1056854..1057240 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  STT55_RS05565 - 1057298..1058105 (-) 808 Protein_1041 GNAT family N-acetyltransferase -
  STT55_RS05570 (STT55_05525) yidA 1058313..1059122 (+) 810 WP_011226081.1 sugar-phosphatase -
  STT55_RS05575 (STT55_05530) - 1059124..1060338 (+) 1215 WP_173940373.1 aminoacyltransferase -
  STT55_RS05580 (STT55_05535) - 1060390..1060751 (-) 362 Protein_1044 YbaN family protein -
  STT55_RS05585 (STT55_05540) vicX 1060811..1061623 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  STT55_RS05590 (STT55_05545) vicK 1061629..1062969 (-) 1341 WP_232979188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STT55_RS05595 (STT55_05550) vicR 1062962..1063669 (-) 708 WP_173940375.1 response regulator YycF Regulator
  STT55_RS05600 (STT55_05555) - 1064196..1064963 (+) 768 WP_173940376.1 amino acid ABC transporter ATP-binding protein -
  STT55_RS05605 (STT55_05560) - 1064975..1065808 (+) 834 WP_022096756.1 transporter substrate-binding domain-containing protein -
  STT55_RS05610 (STT55_05565) - 1065826..1066524 (+) 699 WP_022096755.1 amino acid ABC transporter permease -
  STT55_RS05615 (STT55_05570) - 1066536..1067186 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50780.18 Da        Isoelectric Point: 5.2464

>NTDB_id=511258 STT55_RS05590 WP_232979188.1 1061629..1062969(-) (vicK) [Streptococcus thermophilus strain ST55]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETAIQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=511258 STT55_RS05590 WP_232979188.1 1061629..1062969(-) (vicK) [Streptococcus thermophilus strain ST55]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
TTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAACTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641