Detailed information NTG0510902

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: ST4145_RS05310
• Genome accession: NZ_CP065492
• Coordinates: 1025315..1026022 (-)
• Length: 235 a.a.
• NCBI ID: WP_024009930.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4145
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1020315..1031022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4145_RS05285 (ST4145_05235)	yidA	1020666..1021475 (+)	810	WP_011226081.1	sugar-phosphatase	-
ST4145_RS05290 (ST4145_05240)	-	1021477..1022691 (+)	1215	WP_002953123.1	aminoacyltransferase	-
ST4145_RS05295 (ST4145_05245)	-	1022743..1023104 (-)	362	Protein_987	YbaN family protein	-
ST4145_RS05300 (ST4145_05250)	vicX	1023164..1023973 (-)	810	WP_024704147.1	MBL fold metallo-hydrolase	Regulator
ST4145_RS05305 (ST4145_05255)	vicK	1023982..1025322 (-)	1341	WP_014621665.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ST4145_RS05310 (ST4145_05260)	vicR	1025315..1026022 (-)	708	WP_024009930.1	response regulator YycF	Regulator
ST4145_RS05315 (ST4145_05265)	-	1026546..1027313 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
ST4145_RS05320 (ST4145_05270)	-	1027325..1028158 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
ST4145_RS05325 (ST4145_05275)	-	1028176..1028874 (+)	699	WP_002953144.1	amino acid ABC transporter permease	-
ST4145_RS05330 (ST4145_05280)	-	1028886..1029536 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
ST4145_RS05335 (ST4145_05285)	endA	1029608..1030489 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4145_RS05340 (ST4145_05290)	-	1030551..1030739 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27099.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=510902 ST4145_RS05310 WP_024009930.1 1025315..1026022(-) (vicR) [Streptococcus thermophilus strain 4145]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEILIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=510902 ST4145_RS05310 WP_024009930.1 1025315..1026022(-) (vicR) [Streptococcus thermophilus strain 4145]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTTAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.121	98.723	0.455
covR	Streptococcus salivarius strain HSISS4	45.923	99.149	0.455
scnR	Streptococcus mutans UA159	38.559	100	0.387