Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | STCNRZ887_RS06445 | Genome accession | NZ_CP065491 |
| Coordinates | 1256515..1258008 (-) | Length | 497 a.a. |
| NCBI ID | WP_011227407.1 | Uniprot ID | - |
| Organism | Streptococcus thermophilus strain CNRZ887 | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1238038..1308126 | 1256515..1258008 | within | 0 |
Gene organization within MGE regions
Location: 1238038..1308126
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STCNRZ887_RS06355 (STCNRZ887_06380) | liaF | 1238046..1238744 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| STCNRZ887_RS06360 | - | 1239010..1239165 (-) | 156 | WP_011226290.1 | ion channel | - |
| STCNRZ887_RS06365 (STCNRZ887_06390) | stkP/pknB | 1239802..1241673 (-) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| STCNRZ887_RS06370 (STCNRZ887_06395) | - | 1241673..1242410 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| STCNRZ887_RS06375 (STCNRZ887_06400) | rsmB | 1242454..1243776 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| STCNRZ887_RS06380 (STCNRZ887_06405) | fmt | 1243766..1244701 (-) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| STCNRZ887_RS06385 (STCNRZ887_06410) | - | 1244719..1247115 (-) | 2397 | WP_011226295.1 | primosomal protein N' | - |
| STCNRZ887_RS06390 (STCNRZ887_06415) | rpoZ | 1247257..1247571 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| STCNRZ887_RS06395 (STCNRZ887_06420) | gmk | 1247593..1248222 (-) | 630 | WP_011226296.1 | guanylate kinase | - |
| STCNRZ887_RS06400 (STCNRZ887_06425) | ftsY | 1248455..1249846 (-) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| STCNRZ887_RS06405 (STCNRZ887_06430) | - | 1249860..1250675 (-) | 816 | WP_011227405.1 | Cof-type HAD-IIB family hydrolase | - |
| STCNRZ887_RS06410 (STCNRZ887_06435) | - | 1250668..1251462 (-) | 795 | WP_059257398.1 | HAD family hydrolase | - |
| STCNRZ887_RS06415 (STCNRZ887_06440) | - | 1251645..1252022 (+) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| STCNRZ887_RS06420 (STCNRZ887_06445) | - | 1252027..1252725 (+) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| STCNRZ887_RS06425 (STCNRZ887_06450) | - | 1252737..1253522 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| STCNRZ887_RS06430 (STCNRZ887_06455) | amiF | 1253572..1254501 (-) | 930 | WP_002951426.1 | ATP-binding cassette domain-containing protein | Regulator |
| STCNRZ887_RS06435 (STCNRZ887_06460) | amiE | 1254494..1255579 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| STCNRZ887_RS06440 (STCNRZ887_06465) | amiD | 1255589..1256515 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| STCNRZ887_RS06445 (STCNRZ887_06470) | amiC | 1256515..1258008 (-) | 1494 | WP_011227407.1 | ABC transporter permease | Regulator |
| STCNRZ887_RS06450 (STCNRZ887_06475) | amiA | 1258070..1260037 (-) | 1968 | WP_011225333.1 | peptide ABC transporter substrate-binding protein | Regulator |
| STCNRZ887_RS06455 (STCNRZ887_06480) | - | 1260393..1261642 (+) | 1250 | Protein_1216 | ISL3 family transposase | - |
| STCNRZ887_RS06460 (STCNRZ887_06485) | amiA3 | 1261687..1263660 (-) | 1974 | WP_011226306.1 | peptide ABC transporter substrate-binding protein | Regulator |
| STCNRZ887_RS06465 (STCNRZ887_06490) | - | 1263864..1264054 (-) | 191 | Protein_1218 | IS3 family transposase | - |
| STCNRZ887_RS06470 (STCNRZ887_06495) | - | 1264048..1264449 (-) | 402 | Protein_1219 | ABC transporter ATP-binding protein | - |
| STCNRZ887_RS06475 (STCNRZ887_06500) | - | 1264444..1264804 (-) | 361 | Protein_1220 | TatD family hydrolase | - |
| STCNRZ887_RS06480 (STCNRZ887_06505) | - | 1265154..1266359 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| STCNRZ887_RS06485 (STCNRZ887_06510) | - | 1266405..1267756 (-) | 1352 | Protein_1222 | IS3 family transposase | - |
| STCNRZ887_RS06490 (STCNRZ887_06515) | pta | 1267842..1268825 (-) | 984 | WP_011226315.1 | phosphate acetyltransferase | - |
| STCNRZ887_RS06495 (STCNRZ887_06520) | - | 1268839..1269735 (-) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| STCNRZ887_RS06500 (STCNRZ887_06525) | - | 1269732..1270568 (-) | 837 | WP_041827075.1 | NAD kinase | - |
| STCNRZ887_RS06505 (STCNRZ887_06530) | - | 1270540..1271214 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| STCNRZ887_RS06510 (STCNRZ887_06535) | - | 1271310..1271885 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| STCNRZ887_RS06515 (STCNRZ887_06540) | - | 1272250..1273221 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| STCNRZ887_RS06520 (STCNRZ887_06545) | - | 1273225..1274337 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| STCNRZ887_RS06525 (STCNRZ887_06550) | - | 1274339..1274686 (+) | 348 | WP_011226321.1 | DUF1831 domain-containing protein | - |
| STCNRZ887_RS06530 (STCNRZ887_06555) | - | 1274831..1275490 (+) | 660 | WP_041828288.1 | redox-sensing transcriptional repressor Rex | - |
| STCNRZ887_RS06535 (STCNRZ887_06560) | - | 1275483..1276178 (+) | 696 | WP_011226323.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| STCNRZ887_RS06540 (STCNRZ887_06565) | radC | 1276231..1276917 (-) | 687 | WP_011226324.1 | DNA repair protein RadC | - |
| STCNRZ887_RS06545 (STCNRZ887_06570) | - | 1276966..1278750 (-) | 1785 | WP_011226325.1 | rhamnan synthesis F family protein | - |
| STCNRZ887_RS06550 (STCNRZ887_06575) | - | 1278747..1279802 (-) | 1056 | WP_002948022.1 | glycosyltransferase | - |
| STCNRZ887_RS06555 (STCNRZ887_06580) | - | 1279822..1281027 (-) | 1206 | WP_011226326.1 | ABC transporter ATP-binding protein | - |
| STCNRZ887_RS06560 (STCNRZ887_06585) | - | 1281027..1281836 (-) | 810 | WP_002948020.1 | ABC transporter permease | - |
| STCNRZ887_RS06565 (STCNRZ887_06590) | - | 1281820..1282776 (-) | 957 | WP_011226328.1 | glycosyltransferase family 2 protein | - |
| STCNRZ887_RS06570 (STCNRZ887_06595) | - | 1282773..1283921 (-) | 1149 | WP_041828290.1 | glycosyltransferase family 1 protein | - |
| STCNRZ887_RS06575 (STCNRZ887_06600) | - | 1284030..1285040 (-) | 1011 | WP_011226330.1 | glycosyltransferase family A protein | - |
| STCNRZ887_RS06580 (STCNRZ887_06605) | - | 1285040..1286314 (-) | 1275 | WP_011226331.1 | lipopolysaccharide biosynthesis protein | - |
| STCNRZ887_RS06585 (STCNRZ887_06610) | - | 1286307..1286639 (-) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| STCNRZ887_RS06590 (STCNRZ887_06615) | - | 1286645..1287340 (-) | 696 | WP_173940715.1 | glycosyltransferase family 2 protein | - |
| STCNRZ887_RS06595 (STCNRZ887_06620) | rfbD | 1287417..1288268 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| STCNRZ887_RS06600 (STCNRZ887_06625) | - | 1288345..1289679 (-) | 1335 | WP_041828293.1 | DUF6056 family protein | - |
| STCNRZ887_RS06605 (STCNRZ887_06630) | - | 1289792..1290712 (-) | 921 | WP_116920321.1 | glycosyltransferase family 2 protein | - |
| STCNRZ887_RS06610 (STCNRZ887_06635) | - | 1290772..1292187 (-) | 1416 | WP_096811580.1 | DUF2142 domain-containing protein | - |
| STCNRZ887_RS06615 (STCNRZ887_06640) | - | 1292521..1292856 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| STCNRZ887_RS06620 (STCNRZ887_06645) | rpoD | 1292910..1294019 (-) | 1110 | WP_347114306.1 | RNA polymerase sigma factor RpoD | - |
| STCNRZ887_RS06625 (STCNRZ887_06650) | dnaG | 1294023..1295834 (-) | 1812 | WP_011226339.1 | DNA primase | - |
| STCNRZ887_RS06630 (STCNRZ887_06655) | rpsU | 1296205..1296381 (-) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| STCNRZ887_RS06635 (STCNRZ887_06660) | - | 1296576..1297370 (-) | 795 | WP_011226341.1 | transporter substrate-binding domain-containing protein | - |
| STCNRZ887_RS06640 (STCNRZ887_06665) | - | 1297463..1298572 (-) | 1110 | WP_041828295.1 | aminotransferase | - |
| STCNRZ887_RS06645 (STCNRZ887_06670) | - | 1298919..1299716 (-) | 798 | WP_011226343.1 | transporter substrate-binding domain-containing protein | - |
| STCNRZ887_RS06650 (STCNRZ887_06675) | - | 1299713..1300543 (-) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| STCNRZ887_RS06655 (STCNRZ887_06680) | - | 1300756..1301220 (-) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| STCNRZ887_RS06660 (STCNRZ887_06685) | uvrB | 1301265..1303256 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| STCNRZ887_RS06665 (STCNRZ887_06690) | - | 1303943..1304879 (-) | 937 | Protein_1258 | type II CAAX endopeptidase family protein | - |
| STCNRZ887_RS06670 (STCNRZ887_06695) | - | 1305078..1307288 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| STCNRZ887_RS06675 (STCNRZ887_06700) | - | 1307288..1308028 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55721.59 Da Isoelectric Point: 10.0618
>NTDB_id=510849 STCNRZ887_RS06445 WP_011227407.1 1256515..1258008(-) (amiC) [Streptococcus thermophilus strain CNRZ887]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNGQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=510849 STCNRZ887_RS06445 WP_011227407.1 1256515..1258008(-) (amiC) [Streptococcus thermophilus strain CNRZ887]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCAAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGTTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCAAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGTTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCATAAATATTTGCTTTACTTTAATGG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAACCTTGGTACATCTTACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTACTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATCTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTCGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMG 18311 |
99.799 |
100 |
0.998 |
| amiC | Streptococcus thermophilus LMD-9 |
99.396 |
100 |
0.994 |
| amiC | Streptococcus salivarius strain HSISS4 |
97.183 |
100 |
0.972 |