Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   SIR_RS10130 Genome accession   NC_022246
Coordinates   67910..68908 (+) Length   332 a.a.
NCBI ID   WP_021002295.1    Uniprot ID   T1ZC87
Organism   Streptococcus intermedius B196     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 62910..73908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS10110 (SIR_0074) - 63370..64539 (+) 1170 WP_041787647.1 SIS domain-containing protein -
  SIR_RS10115 (SIR_0075) lacD 64550..65551 (+) 1002 WP_021002292.1 tagatose-bisphosphate aldolase -
  SIR_RS10120 (SIR_0076) - 65594..66640 (+) 1047 WP_021002293.1 aldose epimerase family protein -
  SIR_RS10125 (SIR_0077) - 66736..67503 (-) 768 WP_021002294.1 N-acetylmuramoyl-L-alanine amidase family protein -
  SIR_RS10130 (SIR_0078) ruvB 67910..68908 (+) 999 WP_021002295.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  SIR_RS10135 (SIR_0079) - 68914..69480 (+) 567 WP_021002296.1 nucleotidyltransferase family protein -
  SIR_RS10140 (SIR_0080) - 69792..72518 (+) 2727 WP_021002297.1 Sgo0707 family adhesin -

Sequence

Protein


Download         Length: 332 a.a.        Molecular weight: 37440.81 Da        Isoelectric Point: 4.4306

>NTDB_id=51068 SIR_RS10130 WP_021002295.1 67910..68908(+) (ruvB) [Streptococcus intermedius B196]
MNRMLDNELMGDEELVERTLRPQYLQEYIGQNKVKNQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKSGDLVAILNDLEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGSGETSRSVHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYEETDLTEIVERTAEIFGMEITHEAAEELALRSRGTPRIANRLLKRVRDFAQIMGNGLID
DRITDQALTMLDVDQEGLDYVDQKILKTMIEVYGGGPVGLGTLSVNIAEEQETVEDMYEPYLIQKGFVMRTRTGRVATRK
AYEHLGYEYLEK

Nucleotide


Download         Length: 999 bp        

>NTDB_id=51068 SIR_RS10130 WP_021002295.1 67910..68908(+) (ruvB) [Streptococcus intermedius B196]
ATGAATAGAATGTTAGATAATGAATTGATGGGAGACGAAGAGCTCGTTGAGCGGACATTGCGTCCCCAGTACTTACAAGA
ATATATAGGCCAAAATAAGGTTAAAAATCAACTGAAGATTTTTATTGAGGCAGCCAAGTTGCGAGATGAGGCATTAGATC
ATACCCTACTTTTCGGACCTCCGGGATTGGGTAAAACGACGATGGCTTTTGTGATCGCGAATGAGCTAGGAGTCAATCTC
AAACAGACTTCGGGGCCTGTGATTGAGAAATCGGGCGATTTGGTAGCGATCTTGAATGATCTGGAGCCAGGAGATGTCCT
TTTTATCGATGAAATTCATCGCTTACCCATGTCTGTTGAAGAAGTGCTTTACAGTGCTATGGAAGATTTTTACATTGATA
TTATGATTGGTTCTGGTGAAACCAGTCGCAGTGTTCATTTGGATTTACCACCTTTTACTTTGATTGGGGCAACGACCCGA
GCTGGTATGTTGTCAAATCCCTTGCGGGCTCGCTTTGGTATTACTGGACATATGGAATACTATGAAGAGACGGATTTGAC
CGAGATTGTAGAGCGGACGGCCGAAATCTTTGGGATGGAGATTACACATGAAGCGGCTGAGGAGTTGGCTTTACGTAGCA
GAGGGACCCCTCGAATTGCCAATCGGCTTCTCAAACGCGTACGAGATTTTGCTCAAATCATGGGGAACGGATTGATTGAT
GATCGGATTACCGATCAAGCCCTGACGATGCTTGATGTGGATCAAGAAGGCTTAGACTATGTGGATCAGAAGATTCTTAA
AACCATGATTGAGGTGTATGGAGGCGGACCTGTTGGTTTAGGAACCTTGTCTGTCAATATTGCAGAAGAGCAAGAAACGG
TGGAAGATATGTATGAGCCGTACTTGATTCAGAAAGGCTTTGTTATGCGAACTCGAACAGGACGTGTAGCAACGCGTAAA
GCTTATGAGCATTTGGGTTATGAATATTTGGAAAAGTAG

Domains

Predicted by InterProScan.

RuvB C-terminal winged helix domain (WHD_RuvB)

(256-325)

RuvB AAA lid domain (AAA_lid_4)

(181-254)

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(20-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZC87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Streptococcus pneumoniae TIGR4

90.663

100

0.907
  ruvB Streptococcus pneumoniae R6

90.361

100

0.904
  ruvB Streptococcus pneumoniae D39

90.361

100

0.904
  ruvB Bacillus subtilis subsp. subtilis str. 168

59.202

98.193

0.581
  ruvB Helicobacter pylori 26695

50.915

98.795

0.503
  ruvB Synechocystis sp. PCC 6803

50.645

93.373

0.473

Multiple sequence alignment