Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   ST4078_RS06825 Genome accession   NZ_CP065477
Coordinates   1305169..1307136 (-) Length   655 a.a.
NCBI ID   WP_014621802.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4078     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1307492..1316019 1305169..1307136 flank 356


Gene organization within MGE regions


Location: 1305169..1316019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4078_RS06825 (ST4078_06795) amiA 1305169..1307136 (-) 1968 WP_014621802.1 peptide ABC transporter substrate-binding protein Regulator
  ST4078_RS06830 (ST4078_06800) - 1307492..1308742 (+) 1251 Protein_1296 ISL3 family transposase -
  ST4078_RS06835 (ST4078_06805) amiA3 1308787..1310757 (-) 1971 WP_014608545.1 peptide ABC transporter substrate-binding protein Regulator
  ST4078_RS06840 (ST4078_06810) - 1311062..1312209 (+) 1148 WP_095559415.1 IS3 family transposase -
  ST4078_RS06845 (ST4078_06815) - 1312247..1312431 (-) 185 Protein_1299 IS3 family transposase -
  ST4078_RS06850 - 1312425..1312835 (-) 411 Protein_1300 ATP-binding cassette domain-containing protein -
  ST4078_RS06855 (ST4078_06830) - 1312867..1313181 (-) 315 Protein_1301 TatD family hydrolase -
  ST4078_RS06860 (ST4078_06835) - 1313527..1314732 (+) 1206 WP_011681420.1 L-lactate MFS transporter -

Sequence

Protein


Download         Length: 655 a.a.        Molecular weight: 71809.89 Da        Isoelectric Point: 5.1103

>NTDB_id=510018 ST4078_RS06825 WP_014621802.1 1305169..1307136(-) (amiA) [Streptococcus thermophilus strain 4078]
MKLKKILGITGVALLSVGVLAACSSKSNTSGTTYRNVYSSDPETLDYITSIMGGTKAVLTNGVDGLMEADKYGNLVPSVA
EDWSVSKDGLTYTYKIRKGIKWYTSEGEEYANVTAKDFVTGLKHAADAKSGALYLVQDSIAGLSDYLSGANKDFSNVGVK
AIDDYTLQYTLKKQEPYWNSKTTYGVLFPVNEDFLKNKGKDFGKSTDPTSILYNGPFLLKSLTAKSSIELTKNENYWDKK
NVHFDSIKFSYSDGSDLESIERSFSDGALSIARVFPTSSNYASVEKKYKDNIFYTEPGASTSVIGVNIDRQSYKFSAKKT
DAEKTSTKKALLNKDFRQSINFAIDRTAYQSQVNGKDGAALALRNLFVPYDFVSAGDKTFGDLVTEKMSSYGDEWSGVNF
ADGQEGLYNAEKAKTEFAKAKEALQGEGVQFPVHLDLPVDQSSKLNVAQAQSLKQTIEKSLGSENVVIDINQMSSDDMQN
ATSNAANAAAEDWDISNGVGWGPDYQDPSTYLDILKTTSSENTKAFNGYDDPNNAAAAQVGLKDYDALIDSAASETTDLN
ARYDRYAQAQAWLEDSSLVIPLTVSNGAAPIISRLTPFTGASIQVGDKGSSYLKYVKSQEKVVTKKEYEQSREKWLKERK
ASNEKAQKDLEKHIK

Nucleotide


Download         Length: 1968 bp        

>NTDB_id=510018 ST4078_RS06825 WP_014621802.1 1305169..1307136(-) (amiA) [Streptococcus thermophilus strain 4078]
ATGAAACTTAAAAAAATTCTTGGAATTACGGGTGTAGCCCTTCTAAGTGTAGGTGTGTTAGCGGCTTGTTCATCTAAATC
AAACACTAGCGGAACTACTTATCGTAACGTTTACAGTTCAGATCCAGAAACCTTGGATTATATTACATCAATTATGGGAG
GGACAAAAGCTGTTTTGACTAATGGTGTAGATGGTCTTATGGAAGCGGACAAATATGGTAATCTTGTTCCATCAGTAGCT
GAAGACTGGTCTGTGTCTAAAGATGGTCTTACTTATACCTATAAAATTCGTAAAGGGATCAAATGGTATACTTCTGAAGG
TGAAGAGTACGCTAATGTTACTGCTAAGGACTTTGTAACGGGTCTTAAGCATGCCGCTGATGCCAAATCTGGAGCCCTTT
ATTTGGTACAAGATTCTATTGCTGGATTGTCTGACTACCTTTCTGGTGCCAATAAAGATTTCTCAAATGTTGGCGTTAAA
GCAATAGACGATTACACTCTGCAATACACACTAAAAAAACAGGAACCATACTGGAACTCTAAGACAACCTATGGTGTGCT
CTTCCCAGTTAACGAAGACTTTCTTAAGAACAAAGGGAAAGATTTTGGTAAGTCAACAGACCCAACCTCTATCCTATATA
ACGGTCCTTTCCTTCTTAAATCTTTGACAGCTAAATCATCTATCGAGTTGACTAAGAATGAGAATTATTGGGATAAGAAA
AACGTGCATTTTGACTCTATCAAATTCTCATATTCTGATGGATCGGATCTAGAATCAATAGAACGTAGTTTCTCTGACGG
CGCTCTCAGCATTGCACGTGTCTTCCCTACGAGTTCAAACTATGCATCGGTAGAAAAAAAATATAAAGATAATATTTTTT
ACACAGAACCAGGTGCATCTACATCGGTTATTGGTGTAAACATTGACCGCCAAAGCTATAAATTCTCAGCTAAGAAGACA
GATGCTGAAAAGACATCAACTAAGAAGGCTCTTCTAAACAAAGACTTTCGTCAATCAATCAACTTCGCTATTGATCGTAC
AGCCTATCAATCACAAGTAAACGGTAAAGATGGCGCAGCTCTTGCTCTACGTAACCTTTTTGTTCCTTATGATTTTGTCA
GTGCAGGCGATAAGACCTTTGGTGATCTTGTGACAGAAAAAATGAGCTCTTATGGTGATGAGTGGTCTGGTGTTAACTTT
GCAGATGGTCAAGAGGGTCTCTACAATGCTGAAAAAGCTAAGACTGAGTTTGCCAAAGCCAAAGAGGCTCTTCAAGGAGA
AGGAGTACAATTCCCAGTTCACTTAGACCTTCCAGTTGATCAAAGTTCTAAACTTAATGTTGCTCAAGCTCAATCTTTGA
AACAAACCATTGAAAAATCATTGGGTAGCGAAAATGTTGTTATAGATATTAACCAAATGTCATCTGATGATATGCAAAAT
GCGACTAGTAATGCGGCAAATGCTGCAGCAGAAGACTGGGATATTTCTAACGGTGTGGGTTGGGGTCCAGACTATCAAGA
TCCATCAACTTATCTTGATATCTTAAAAACAACATCAAGTGAAAATACCAAGGCTTTCAATGGTTATGATGATCCAAACA
ATGCAGCAGCAGCCCAAGTAGGTCTTAAAGATTATGATGCCTTGATTGATTCAGCAGCTTCAGAAACAACAGACCTCAAC
GCTCGTTACGACCGTTATGCTCAAGCCCAAGCTTGGTTGGAAGATAGCTCTCTTGTCATTCCATTGACTGTTAGTAACGG
TGCAGCACCGATTATCTCACGTTTGACACCATTTACGGGTGCTAGCATACAGGTGGGTGATAAGGGCTCATCCTACCTCA
AATATGTGAAATCACAAGAAAAAGTAGTTACTAAGAAAGAATATGAACAAAGTCGTGAAAAATGGCTTAAAGAAAGGAAA
GCATCTAACGAAAAAGCTCAAAAAGATCTTGAGAAACACATTAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(75-520)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

89.177

100

0.893
  amiA3 Streptococcus thermophilus LMD-9

87.367

100

0.876
  amiA3 Streptococcus thermophilus LMG 18311

87.215

100

0.875