Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   I5W22_RS07765 Genome accession   NZ_CP065431
Coordinates   1568793..1569437 (+) Length   214 a.a.
NCBI ID   WP_012027589.1    Uniprot ID   A0A0M9FEX3
Organism   Streptococcus suis strain YP20190405     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1563793..1574437
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5W22_RS07745 (I5W22_07745) pflA 1564940..1565731 (-) 792 WP_012027587.1 pyruvate formate-lyase-activating protein -
  I5W22_RS07750 (I5W22_07750) - 1565852..1567189 (-) 1338 WP_004194632.1 hemolysin family protein -
  I5W22_RS07755 (I5W22_07755) - 1567322..1568101 (+) 780 WP_012027588.1 ABC transporter ATP-binding protein -
  I5W22_RS07760 (I5W22_07760) - 1568117..1568671 (-) 555 WP_004194627.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  I5W22_RS07765 (I5W22_07765) cclA/cilC 1568793..1569437 (+) 645 WP_012027589.1 prepilin peptidase Machinery gene
  I5W22_RS07770 (I5W22_07770) - 1569545..1571005 (+) 1461 WP_012027590.1 nicotinate phosphoribosyltransferase -
  I5W22_RS07775 (I5W22_07775) nadE 1571018..1571842 (+) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -
  I5W22_RS07780 (I5W22_07780) - 1573138..1573665 (-) 528 WP_012027591.1 VanZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24215.33 Da        Isoelectric Point: 8.4760

>NTDB_id=509578 I5W22_RS07765 WP_012027589.1 1568793..1569437(+) (cclA/cilC) [Streptococcus suis strain YP20190405]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT

Nucleotide


Download         Length: 645 bp        

>NTDB_id=509578 I5W22_RS07765 WP_012027589.1 1568793..1569437(+) (cclA/cilC) [Streptococcus suis strain YP20190405]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCCTGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGATTGGAATTCTTAGCCGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAGCATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATAGCTCTGATACTCTCCCAGCTCA
ACTGGCTTTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTATTTCTTTCAAGTATTCCTATCATTCTGTGCA
CCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FEX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

47.17

99.065

0.467
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453