Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I2439_RS08720 Genome accession   NZ_CP065191
Coordinates   1822138..1822824 (-) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1817138..1827824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS08700 (HIEAAJJG_01761) dnaI 1817904..1818812 (-) 909 WP_012680068.1 primosomal protein DnaI -
  I2439_RS08705 (HIEAAJJG_01762) - 1818813..1819976 (-) 1164 WP_172452942.1 helicase loader -
  I2439_RS08710 (HIEAAJJG_01763) nrdR 1819960..1820454 (-) 495 WP_012516251.1 transcriptional regulator NrdR -
  I2439_RS08715 (HIEAAJJG_01764) - 1820644..1822134 (-) 1491 WP_115251292.1 HAMP domain-containing histidine kinase -
  I2439_RS08720 (HIEAAJJG_01765) covR 1822138..1822824 (-) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  I2439_RS08725 (HIEAAJJG_01766) - 1823008..1823541 (-) 534 WP_111678519.1 YceD family protein -
  I2439_RS08730 (HIEAAJJG_01767) htpX 1823830..1824723 (-) 894 WP_111678521.1 zinc metalloprotease HtpX -
  I2439_RS08735 (HIEAAJJG_01768) - 1824755..1825312 (-) 558 WP_111678523.1 LemA family protein -
  I2439_RS08740 (HIEAAJJG_01769) rsmG 1825449..1826162 (+) 714 WP_111678525.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=507843 I2439_RS08720 WP_012516253.1 1822138..1822824(-) (covR) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=507843 I2439_RS08720 WP_012516253.1 1822138..1822824(-) (covR) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCACTTGAGCTACAGCATGAGGGTTA
CGAGGTAACCGTTGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGGTTTGAAGTGACACGTCGTTTGCAAACAGAAAAAACGACTTACATCATGATGATGACA
GCGCGTGATTCTATTATGGACGTTGTAGCCGGCTTGGATCGTGGTGCTGATGATTACATCGTGAAGCCATTTGCCATTGA
AGAATTGCTGGCACGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTGTCTAACGTTTGGAAATATGA
CGAGGCTGTTGAGACCAATGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATAGATATCCCTGGGAAAGAATCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425