Detailed information NTG0050769

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SMULJ23_RS06985
• Genome accession: NC_017768
• Coordinates: 1441701..1443935 (-)
• Length: 744 a.a.
• NCBI ID: WP_044560631.1
• Uniprot ID: -
• Organism: Streptococcus mutans LJ23
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1436701..1448935

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMULJ23_RS10205 (SMULJ23_1360)	-	1437302..1438366 (-)	1065	WP_014678131.1	serine hydrolase	-
SMULJ23_RS06970 (SMULJ23_1361)	sodA	1438919..1439530 (-)	612	WP_002261912.1	superoxide dismutase SodA	-
SMULJ23_RS06975 (SMULJ23_1362)	holA	1439677..1440717 (-)	1041	WP_002270598.1	DNA polymerase III subunit delta	-
SMULJ23_RS06980 (SMULJ23_1363)	-	1440889..1441515 (-)	627	WP_002264731.1	DUF805 domain-containing protein	-
SMULJ23_RS06985 (SMULJ23_1364)	comEC/celB	1441701..1443935 (-)	2235	WP_044560631.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SMULJ23_RS06990 (SMULJ23_1365)	-	1443925..1444605 (-)	681	WP_014678133.1	helix-hairpin-helix domain-containing protein	-
SMULJ23_RS06995 (SMULJ23_1366)	-	1444745..1445497 (-)	753	WP_014678134.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SMULJ23_RS07000 (SMULJ23_1367)	-	1445636..1446571 (+)	936	WP_014678135.1	polysaccharide deacetylase family protein	-
SMULJ23_RS07005 (SMULJ23_1368)	-	1446656..1447168 (+)	513	WP_002289092.1	HXXEE domain-containing protein	-
SMULJ23_RS07010 (SMULJ23_1369)	-	1447214..1448233 (+)	1020	WP_014678136.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85519.01 Da
• Isoelectric Point: 10.0841

>NTDB_id=50769 SMULJ23_RS06985 WP_044560631.1 1441701..1443935(-) (comEC/celB) [Streptococcus mutans LJ23]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSVNGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSPLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRMRISDANAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKKNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=50769 SMULJ23_RS06985 WP_044560631.1 1441701..1443935(-) (comEC/celB) [Streptococcus mutans LJ23]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTGTCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTCACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTACCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACCCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTAGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACTTTTGGACAGACTGATAAATGGCGGATGCGTATCAGTGATGCTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAAAAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

• Competence protein (Competence) (214-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	51.282	99.597	0.511
comEC/celB	Streptococcus mitis NCTC 12261	51.078	99.731	0.509
comEC/celB	Streptococcus pneumoniae TIGR4	50.806	100	0.508
comEC/celB	Streptococcus pneumoniae Rx1	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae D39	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae R6	50.134	100	0.501
comEC	Lactococcus lactis subsp. cremoris KW2	46.309	100	0.464