Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMULJ23_RS01355 Genome accession   NC_017768
Coordinates   301917..302609 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans LJ23     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 296917..307609
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMULJ23_RS01335 (SMULJ23_0248) - 297030..299642 (-) 2613 WP_014677752.1 ABC transporter permease -
  SMULJ23_RS01340 (SMULJ23_0249) - 299644..300351 (-) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  SMULJ23_RS01345 (SMULJ23_0250) - 300459..301034 (+) 576 WP_014677753.1 TetR/AcrR family transcriptional regulator -
  SMULJ23_RS01350 (SMULJ23_0251) - 301027..301563 (+) 537 WP_014677754.1 YceD family protein -
  SMULJ23_RS01355 (SMULJ23_0252) covR 301917..302609 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  SMULJ23_RS01360 (SMULJ23_0253) nrdR 302978..303469 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  SMULJ23_RS01365 (SMULJ23_0254) - 303456..304625 (+) 1170 WP_002276047.1 DnaD domain protein -
  SMULJ23_RS01370 (SMULJ23_0255) dnaI 304626..305525 (+) 900 WP_002265451.1 primosomal protein DnaI -
  SMULJ23_RS01375 (SMULJ23_0256) der 305538..306848 (+) 1311 WP_002292004.1 ribosome biogenesis GTPase Der -
  SMULJ23_RS01380 (SMULJ23_0257) - 306923..307549 (+) 627 WP_014677755.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=50739 SMULJ23_RS01355 WP_002262121.1 301917..302609(+) (covR) [Streptococcus mutans LJ23]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=50739 SMULJ23_RS01355 WP_002262121.1 301917..302609(+) (covR) [Streptococcus mutans LJ23]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment