Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   VB13_RS05270 Genome accession   NZ_CP077685
Coordinates   1066755..1067717 (-) Length   320 a.a.
NCBI ID   WP_009880653.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M49 591     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1061755..1072717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS05255 (VB13_05425) - 1062590..1063297 (-) 708 WP_219050252.1 O-methyltransferase -
  VB13_RS05260 (VB13_05430) - 1063363..1064559 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  VB13_RS05265 (VB13_05435) pepF 1064937..1066742 (-) 1806 WP_009880654.1 oligoendopeptidase F Regulator
  VB13_RS05270 (VB13_05440) coiA 1066755..1067717 (-) 963 WP_009880653.1 competence protein CoiA Machinery gene
  VB13_RS05275 (VB13_05445) - 1068014..1068730 (-) 717 WP_009880652.1 pseudouridine synthase -
  VB13_RS05280 (VB13_05450) nagB 1068849..1069553 (-) 705 WP_009880651.1 glucosamine-6-phosphate deaminase -
  VB13_RS05285 (VB13_05455) queA 1069755..1070783 (+) 1029 WP_002995782.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  VB13_RS05290 (VB13_05460) - 1070790..1072010 (+) 1221 WP_012560799.1 DUF3114 domain-containing protein -
  VB13_RS05295 (VB13_05465) - 1072124..1072714 (-) 591 WP_012560800.1 serine hydrolase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37813.30 Da        Isoelectric Point: 10.2848

>NTDB_id=506873 VB13_RS05270 WP_009880653.1 1066755..1067717(-) (coiA) [Streptococcus pyogenes strain M49 591]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RIEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=506873 VB13_RS05270 WP_009880653.1 1066755..1067717(-) (coiA) [Streptococcus pyogenes strain M49 591]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAATAGAAGCTGTTTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTGCTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCATAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACATCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.024

100

0.4