Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I2437_RS05135 Genome accession   NZ_CP065061
Coordinates   1053706..1055016 (-) Length   436 a.a.
NCBI ID   WP_206157698.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ33     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1048706..1060016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2437_RS05095 (IEMOCGPF_01020) coaA 1048980..1049900 (+) 921 WP_164336949.1 type I pantothenate kinase -
  I2437_RS05100 (IEMOCGPF_01021) rpsT 1049969..1050202 (+) 234 WP_037578328.1 30S ribosomal protein S20 -
  I2437_RS05105 (IEMOCGPF_01022) - 1050401..1050685 (-) 285 WP_165628099.1 hypothetical protein -
  I2437_RS05110 (IEMOCGPF_01023) - 1050705..1051106 (-) 402 WP_206157696.1 hypothetical protein -
  I2437_RS05115 (IEMOCGPF_01024) - 1051103..1052302 (-) 1200 WP_206157697.1 hypothetical protein -
  I2437_RS05120 (IEMOCGPF_01025) - 1052304..1052687 (-) 384 WP_165628096.1 hypothetical protein -
  I2437_RS05125 (IEMOCGPF_01026) - 1052611..1052901 (-) 291 WP_165628095.1 hypothetical protein -
  I2437_RS05130 (IEMOCGPF_01027) - 1052902..1053321 (-) 420 WP_165628094.1 hypothetical protein -
  I2437_RS05135 (IEMOCGPF_01028) ciaH 1053706..1055016 (-) 1311 WP_206157698.1 HAMP domain-containing sensor histidine kinase Regulator
  I2437_RS05140 (IEMOCGPF_01029) ciaR 1055009..1055683 (-) 675 WP_012515548.1 response regulator transcription factor Regulator
  I2437_RS05145 (IEMOCGPF_01030) - 1056102..1058639 (-) 2538 WP_165627478.1 M1 family metallopeptidase -
  I2437_RS05150 (IEMOCGPF_01031) phoU 1058869..1059522 (-) 654 WP_206158033.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49634.33 Da        Isoelectric Point: 9.6507

>NTDB_id=506607 I2437_RS05135 WP_206157698.1 1053706..1055016(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRMDKVRTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=506607 I2437_RS05135 WP_206157698.1 1053706..1055016(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGACGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAGTCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAATGGATAAGGTAAGGACACGCCAAAAAGGA
GGGTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.437

100

0.576
  ciaH Streptococcus pneumoniae Rx1

50.917

100

0.509
  ciaH Streptococcus pneumoniae D39

50.917

100

0.509
  ciaH Streptococcus pneumoniae R6

50.917

100

0.509
  ciaH Streptococcus pneumoniae TIGR4

50.917

100

0.509