Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SCI_RS05975 Genome accession   NC_022238
Coordinates   1208331..1209683 (-) Length   450 a.a.
NCBI ID   WP_006268651.1    Uniprot ID   F9P8V4
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1203331..1214683
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS05965 (SCI_1175) rnc 1206332..1207030 (-) 699 WP_003068697.1 ribonuclease III -
  SCI_RS10755 - 1207166..1207431 (-) 266 Protein_1179 YbaN family protein -
  SCI_RS05970 (SCI_1176) vicX 1207526..1208329 (-) 804 WP_006268738.1 MBL fold metallo-hydrolase Regulator
  SCI_RS05975 (SCI_1177) micB 1208331..1209683 (-) 1353 WP_006268651.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SCI_RS05980 (SCI_1178) yycF 1209676..1210377 (-) 702 WP_003035055.1 response regulator YycF -
  SCI_RS05985 (SCI_1179) - 1210678..1211010 (-) 333 WP_006268722.1 hypothetical protein -
  SCI_RS05990 (SCI_1180) - 1211037..1212350 (-) 1314 WP_006268747.1 glycosyltransferase family 4 protein -
  SCI_RS05995 (SCI_1181) - 1212352..1213350 (-) 999 WP_020997876.1 glycosyltransferase family 4 protein -
  SCI_RS06000 (SCI_1182) ccpA 1213442..1214446 (-) 1005 WP_003068684.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51407.70 Da        Isoelectric Point: 4.7289

>NTDB_id=50633 SCI_RS05975 WP_006268651.1 1208331..1209683(-) (micB) [Streptococcus constellatus subsp. pharyngis C1050]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRRLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=50633 SCI_RS05975 WP_006268651.1 1208331..1209683(-) (micB) [Streptococcus constellatus subsp. pharyngis C1050]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCGATTGAATCAAAAAGTGAAGGATTTAATCGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCGGAAATTACTGATATTACAAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTGTCCTATATGACAGATGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAGTCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGATGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTACGAAATTATCCGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAGATCACAGTGAGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCCTAGGGATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCCCAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAACATAACGGATTTATCTGGGCAAAGAGCGAGTACGGCAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P8V4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

70.905

90.889

0.644

Multiple sequence alignment