Detailed information NTG0050635

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SCI_RS06000
• Genome accession: NC_022238
• Coordinates: 1213442..1214446 (-)
• Length: 334 a.a.
• NCBI ID: WP_003068684.1
• Uniprot ID: U2XVW3
• Organism: Streptococcus constellatus subsp. pharyngis C1050
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1208442..1219446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCI_RS05980 (SCI_1178)	yycF	1209676..1210377 (-)	702	WP_003035055.1	response regulator YycF	-
SCI_RS05985 (SCI_1179)	-	1210678..1211010 (-)	333	WP_006268722.1	hypothetical protein	-
SCI_RS05990 (SCI_1180)	-	1211037..1212350 (-)	1314	WP_006268747.1	glycosyltransferase family 4 protein	-
SCI_RS05995 (SCI_1181)	-	1212352..1213350 (-)	999	WP_020997876.1	glycosyltransferase family 4 protein	-
SCI_RS06000 (SCI_1182)	ccpA	1213442..1214446 (-)	1005	WP_003068684.1	catabolite control protein A	Regulator
SCI_RS06005 (SCI_1183)	-	1214711..1215793 (+)	1083	WP_020997877.1	Xaa-Pro peptidase family protein	-
SCI_RS06010 (SCI_1184)	-	1216316..1216897 (-)	582	WP_006268725.1	class I SAM-dependent methyltransferase	-
SCI_RS06015 (SCI_1185)	galE	1217216..1218235 (-)	1020	WP_020997878.1	UDP-glucose 4-epimerase GalE	-
SCI_RS06020 (SCI_1186)	rfbB	1218270..1219316 (-)	1047	WP_020997879.1	dTDP-glucose 4,6-dehydratase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 37056.22 Da
• Isoelectric Point: 6.1741

>NTDB_id=50635 SCI_RS06000 WP_003068684.1 1213442..1214446(-) (ccpA) [Streptococcus constellatus subsp. pharyngis C1050]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVERLTKNNKKIAFVSGPLVDDINGKIRLIGYKEALKKAKLSYSEGLVFESKYSYEDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKGVNIPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERRSTRK

Nucleotide

• Length: 1005 bp

>NTDB_id=50635 SCI_RS06000 WP_003068684.1 1213442..1214446(-) (ccpA) [Streptococcus constellatus subsp. pharyngis C1050]
ATGAACACAGACGATACTGTAACGATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTCGT
AAACGGCAATAAAAATGTAAAGGAAAATACAAGAAAAAAAGTCTTGGAAGTCATTGATCGCCTTGACTATCGACCAAATG
CAGTTGCTCGTGGACTTGCCAGTAAGAAAACGACAACAGTAGGAGTTGTCATTCCAAACATTACAAGCAGTTATTTTGCA
ACGCTTGCGAAAGGAATTGATGACATCGCAGAGATGTATAAGTATAATATTGTTTTGGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCTGTTGTCAATACCTTGTTCTCAAAACAAGTGGACGGCATTATCTTTATGGGATATCATCTAACAGAAA
AGATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCGGTTGTACTTGCAGGAACGGTTGACGTGGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCAGTAGAGCGCCTCACTAAAAACAATAAAAAAATTGCTTTTGTGAG
TGGACCTTTGGTAGATGATATAAATGGTAAGATTCGTTTAATTGGTTACAAAGAAGCGTTGAAAAAAGCAAAACTTTCTT
ATAGTGAAGGGCTTGTCTTTGAGTCTAAATACAGCTATGAGGATGGCTATCAATTGGCAGAGCGTGTCATTGCTTCTAAA
GCGACAGCAGCCTTTGTGACTGGTGATGAACTGGCAGCTGGATTGTTAAATGGCTTATCAGACAAAGGTGTAAATATACC
AGAAGATTTTGAAATCATTACTAGTGATGATTCGCAGGTAGCACGTTTTACTCGTCCAAATTTGACGACAATTGGACAAC
CTTTGTACGATCTTGGTGCGATTAGTATGCGCATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTG
GTGTTAGCTCATGGTCTTATTGAGCGCCGTTCAACAAGGAAGTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: U2XVW3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	90.719	100	0.907
ccpA	Streptococcus pneumoniae D39	87.725	100	0.877
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.308	99.102	0.578