Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HCW_RS00285 Genome accession   NC_017737
Coordinates   58674..58955 (-) Length   93 a.a.
NCBI ID   WP_014660231.1    Uniprot ID   I0EK86
Organism   Helicobacter cetorum MIT 00-7128     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 53674..63955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCW_RS00270 (HCW_00280) - 54173..55585 (-) 1413 WP_014660229.1 COG3014 family protein -
  HCW_RS00275 - 56019..58407 (-) 2389 Protein_54 VirB4 family type IV secretion/conjugal transfer ATPase -
  HCW_RS00280 (HCW_00295) comB3 58413..58673 (-) 261 WP_014660230.1 hypothetical protein Machinery gene
  HCW_RS00285 (HCW_00300) comB2 58674..58955 (-) 282 WP_014660231.1 TrbC/VirB2 family protein Machinery gene
  HCW_RS00290 (HCW_00305) - 59218..60048 (-) 831 WP_014660232.1 DUF5718 family protein -
  HCW_RS00295 (HCW_00310) - 60170..61222 (-) 1053 WP_014660233.1 MnmA/TRMU family protein -
  HCW_RS00300 (HCW_00315) dnaG 61219..62937 (-) 1719 WP_014660234.1 DNA primase -
  HCW_RS00305 (HCW_00320) groES 63210..63557 (+) 348 WP_014660235.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10600.85 Da        Isoelectric Point: 10.0022

>NTDB_id=50465 HCW_RS00285 WP_014660231.1 58674..58955(-) (comB2) [Helicobacter cetorum MIT 00-7128]
MSALFLRIMILMTISFSNLFAEGLEGFFNALESQLKSPTAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVLGIFLFF
KAPSLANWFMGVF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=50465 HCW_RS00285 WP_014660231.1 58674..58955(-) (comB2) [Helicobacter cetorum MIT 00-7128]
ATGAGTGCTTTATTTTTAAGAATAATGATTTTAATGACAATTAGCTTTTCAAATTTGTTTGCAGAAGGGTTAGAAGGGTT
TTTCAACGCTTTAGAAAGTCAGCTTAAAAGCCCTACAGCTAAAGGCATTTTAATGGTGATTTTTATAGGGATTGCTATTT
ATGTATGGAGGAATTTGGATAGGTGGAAAGAAATTCTATTTACTATACTTGGTGTGGTGCTTGGGATTTTTCTCTTTTTT
AAAGCCCCAAGTTTGGCTAATTGGTTTATGGGGGTGTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(5-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0EK86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

84.946

100

0.849

Multiple sequence alignment