Detailed information NTG0504646

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IXH55_RS08170
• Genome accession: NZ_CP064772
• Coordinates: 1702124..1703011 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TCH32767
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1697124..1708011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IXH55_RS08140 (IXH55_08095)	-	1697856..1698617 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
IXH55_RS08145 (IXH55_08100)	-	1698862..1699317 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IXH55_RS14155	-	1699439..1699540 (+)	102	WP_000731976.1	SE2200 family small protein	-
IXH55_RS08155 (IXH55_08110)	-	1699600..1701024 (-)	1425	WP_000953755.1	alkaline phosphatase	-
IXH55_RS08160 (IXH55_08115)	-	1701222..1701422 (+)	201	WP_000604730.1	hypothetical protein	-
IXH55_RS08165 (IXH55_08120)	braR	1701448..1702113 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IXH55_RS08170 (IXH55_08125)	braS	1702124..1703011 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IXH55_RS08175 (IXH55_08130)	-	1703119..1703874 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IXH55_RS08180 (IXH55_08135)	-	1703871..1705871 (+)	2001	WP_000776750.1	ABC transporter permease	-
IXH55_RS08185 (IXH55_08140)	-	1706530..1706643 (+)	114	Protein_1613	hypothetical protein	-
IXH55_RS08190 (IXH55_08145)	-	1707025..1707285 (+)	261	WP_001791974.1	hypothetical protein	-
IXH55_RS08195 (IXH55_08150)	-	1707295..1707792 (+)	498	WP_001065268.1	glutathione peroxidase	-
IXH55_RS08200 (IXH55_08155)	-	1707900..1707992 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=504646 IXH55_RS08170 WP_000143425.1 1702124..1703011(+) (braS) [Staphylococcus aureus strain TCH32767]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=504646 IXH55_RS08170 WP_000143425.1 1702124..1703011(+) (braS) [Staphylococcus aureus strain TCH32767]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1