Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPB14_RS00215 Genome accession   NC_017733
Coordinates   37510..38253 (+) Length   247 a.a.
NCBI ID   WP_001208391.1    Uniprot ID   -
Organism   Helicobacter pylori HUP-B14     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32510..43253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPB14_RS00190 (HPB14_00165) panD 34668..35021 (+) 354 WP_000142235.1 aspartate 1-decarboxylase -
  HPB14_RS00195 (HPB14_00170) - 35024..35326 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  HPB14_RS00200 (HPB14_00175) - 35326..36321 (+) 996 WP_000468427.1 PDZ domain-containing protein -
  HPB14_RS00205 (HPB14_00180) comB6 36329..37384 (+) 1056 WP_000786655.1 P-type conjugative transfer protein TrbL Machinery gene
  HPB14_RS00210 (HPB14_00185) comB7 37400..37513 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HPB14_RS00215 (HPB14_00190) comB8 37510..38253 (+) 744 WP_001208391.1 type IV secretion system protein Machinery gene
  HPB14_RS00220 (HPB14_00195) comB9 38253..39272 (+) 1020 WP_014658396.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPB14_RS00225 (HPB14_00200) comB10 39265..40401 (+) 1137 WP_001045836.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPB14_RS00230 (HPB14_00205) - 40471..41883 (+) 1413 WP_000694865.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPB14_RS00235 (HPB14_00210) gmd 41925..43070 (+) 1146 WP_000659798.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28781.97 Da        Isoelectric Point: 8.9604

>NTDB_id=50426 HPB14_RS00215 WP_001208391.1 37510..38253(+) (comB8) [Helicobacter pylori HUP-B14]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=50426 HPB14_RS00215 WP_001208391.1 37510..38253(+) (comB8) [Helicobacter pylori HUP-B14]
ATGAGAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTATTTAGATTAGAGAGAAACCGCTTGAAAATCGCTT
ATAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATTTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTAACGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAGATCGTATTGAGTTATCTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCACCGACTAACAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

98.381

100

0.984

Multiple sequence alignment