Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   KPA27_RS00325 Genome accession   NZ_CP076517
Coordinates   55071..55970 (+) Length   299 a.a.
NCBI ID   WP_012774888.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50071..60970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS10510 - 50770..50964 (+) 195 Protein_40 ATP-binding cassette domain-containing protein -
  KPA27_RS00300 (KPA27_00300) - 51007..51870 (+) 864 Protein_41 ABC transporter ATP-binding protein -
  KPA27_RS00305 (KPA27_00305) - 51972..52145 (+) 174 WP_014735240.1 hypothetical protein -
  KPA27_RS00310 (KPA27_00310) ruvB 52440..53441 (+) 1002 WP_024402117.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  KPA27_RS00315 (KPA27_00315) - 53441..54187 (+) 747 WP_024402116.1 GNAT family N-acetyltransferase -
  KPA27_RS00320 (KPA27_00320) - 54189..54824 (+) 636 WP_024402115.1 HAD-IA family hydrolase -
  KPA27_RS00325 (KPA27_00325) comR 55071..55970 (+) 900 WP_012774888.1 helix-turn-helix domain-containing protein Regulator
  KPA27_RS00330 (KPA27_00330) - 56606..57544 (-) 939 WP_024402114.1 IS4 family transposase -
  KPA27_RS00335 (KPA27_00335) - 57681..58901 (+) 1221 WP_172005365.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  KPA27_RS00340 (KPA27_00340) - 59092..60615 (+) 1524 WP_141587958.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35405.30 Da        Isoelectric Point: 4.6492

>NTDB_id=503115 KPA27_RS00325 WP_012774888.1 55071..55970(+) (comR) [Streptococcus suis strain 39565]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=503115 KPA27_RS00325 WP_012774888.1 55071..55970(+) (comR) [Streptococcus suis strain 39565]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGCG
TAAATATATTAGGAAGCAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

100

100

1
  comR Streptococcus suis 05ZYH33

100

100

1
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371