Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A7A17_RS18670 Genome accession   NZ_CP076264
Coordinates   3766312..3767550 (-) Length   412 a.a.
NCBI ID   WP_257117329.1    Uniprot ID   -
Organism   Escherichia coli strain NADC1036     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3761312..3772550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A17_RS18650 (A7A17_18605) dam 3761924..3762760 (-) 837 WP_000742143.1 adenine-specific DNA-methyltransferase -
  A7A17_RS18655 (A7A17_18610) damX 3762867..3764153 (-) 1287 WP_000343178.1 cell division protein DamX -
  A7A17_RS18660 (A7A17_18615) aroB 3764245..3765333 (-) 1089 WP_000439846.1 3-dehydroquinate synthase -
  A7A17_RS18665 (A7A17_18620) aroK 3765390..3765911 (-) 522 WP_000818618.1 shikimate kinase AroK -
  A7A17_RS18670 (A7A17_18625) comE 3766312..3767550 (-) 1239 WP_257117329.1 DNA uptake porin HofQ Machinery gene
  A7A17_RS18675 (A7A17_18630) hofP 3767462..3767866 (-) 405 WP_001264141.1 DNA utilization protein HofP -
  A7A17_RS18680 (A7A17_18635) hofO 3767856..3768296 (-) 441 WP_001055760.1 DNA utilization protein HofO -
  A7A17_RS18685 (A7A17_18640) hofN 3768280..3768819 (-) 540 WP_001069315.1 DNA utilization protein HofN -
  A7A17_RS18690 (A7A17_18645) hofM 3768819..3769598 (-) 780 WP_001315880.1 DNA utilization protein HofM -
  A7A17_RS18695 (A7A17_18650) mrcA 3769718..3772270 (+) 2553 WP_000673804.1 peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 44743.30 Da        Isoelectric Point: 6.1173

>NTDB_id=501287 A7A17_RS18670 WP_257117329.1 3766312..3767550(-) (comE) [Escherichia coli strain NADC1036]
MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGL
ITRQEGNILSVHSIAWQNDNIARQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNIGRIN
GRLLDLELSALEQKQQLDIIASPRLLALHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKL
HISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERREL
VVFITPRLVSSE

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=501287 A7A17_RS18670 WP_257117329.1 3766312..3767550(-) (comE) [Escherichia coli strain NADC1036]
ATGAAGCAATGGATAGCCGCACTACTGTTGATGCTGATACCCGGCGTACAGGCGGCAAAGCCGCAAAAAGTGACGCTGAT
GGTGGATGACGTTCCGGTGGCTCAGGTGTTGCAGGCGCTGGCTGAACAGGAGAAGTTGAACCTGGTCGTGTCGCCAGACG
TCAGCGGTACGGTGTCGTTACATCTAACAGATGTTCCCTGGAAGCAGGCACTACAAACTGTAGTGAAAAGCGCCGGGCTG
ATAACGCGCCAGGAGGGCAACATTCTCTCAGTGCATTCTATTGCCTGGCAGAATGACAATATCGCCCGCCAGGAGGCGGA
GCAGGCGCGGGCGCAGGCAAATCTGCCGCTGGAAAATCGCAGTATAACCCTGCAATACGCCGACGCGGGAGAACTGGCGA
AAGCGGGGGAGAAGCTACTGAGTGCCAAAGGGAGTATGACCGTCGATAAACGCACCAATCGCCTTTTGCTACGAGATAAC
AAAACGGCGTTAAGCGCGCTTGAACAGTGGGTAGCGCAAATGGATCTTCCGGTCGGGCAGGTTGAGCTGTCGGCGCATAT
TGTCACCATTAATGAAAAAAGTTTGCGTGAGTTAGGCGTGAAATGGACGCTGGCCGATGCGCAACACGCTGGTGGTGTTG
GGCAAGTCACCACGCTTGGTAGCGACCTCTCCGTAGCGACGGCGACAACGCATGTCGGTTTTAACATTGGGCGCATCAAC
GGACGTTTGCTGGATCTTGAGCTTTCCGCGCTCGAACAAAAACAGCAGCTGGATATTATCGCCAGTCCGCGTCTGCTGGC
CTTACATCTTCAGCCTGCCAGTATTAAACAGGGGAGCGAAATTCCATATCAGGTTTCCAGCGGGGAAAGTGGCGCGACGT
CGGTGGAATTTAAAGAGGCCGTCCTGGGGATGGAGGTCACGCCCACGGTGTTACAAAAAGGTCGCATCCGGCTGAAATTA
CACATCAGCCAGAACGTTCCGGGGCAGGTGCTACAGCAGGCCGATGGCGAAGTGCTGGCGATTGATAAGCAGGAGATCGA
AACGCAGGTCGAGGTCAAAAGCGGAGAAACGTTGGCGCTGGGCGGCATTTTTACCCGTAAAAATAAATCGGGTCAGGATA
GCGTGCCGTTGCTTGGCGACATTCCCTGGTTCGGGCAATTATTTCGTCATGACGGAAAAGAAGATGAACGACGCGAGTTA
GTGGTGTTTATCACGCCACGACTGGTTTCCAGTGAGTAA

Domains

Predicted by InterProScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(120-179)

Bacterial type II and III secretion system protein (Secretin)

(250-409)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

37.156

100

0.393
  comE Haemophilus influenzae 86-028NP

36.927

100

0.391
  pilQ Vibrio campbellii strain DS40M4

38.242

100

0.391
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.772

100

0.379
  pilQ Vibrio cholerae strain A1552

37.772

100

0.379
  comE Glaesserella parasuis strain SC1401

35.952

100

0.367