Detailed information NTG0501097

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: IUJ46_RS08955
• Genome accession: NZ_CP064364
• Coordinates: 1735984..1736418 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain PartK-Spyogenes-RM8376
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1730984..1741418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ46_RS08925 (IUJ46_08880)	-	1732653..1733018 (+)	366	WP_002986560.1	DUF1033 family protein	-
IUJ46_RS08930 (IUJ46_08885)	comYA	1733111..1734049 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
IUJ46_RS08935 (IUJ46_08890)	comYB	1733985..1735019 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
IUJ46_RS08940 (IUJ46_08895)	comYC	1735021..1735347 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
IUJ46_RS08945 (IUJ46_08900)	comGD	1735322..1735750 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
IUJ46_RS08950 (IUJ46_08905)	comGE	1735707..1735991 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
IUJ46_RS08955 (IUJ46_08910)	comYF	1735984..1736418 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
IUJ46_RS08960 (IUJ46_08915)	comGG	1736402..1736728 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
IUJ46_RS08965 (IUJ46_08920)	comYH	1736826..1737779 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
IUJ46_RS08970 (IUJ46_08925)	-	1737838..1739034 (+)	1197	WP_010921803.1	acetate kinase	-
IUJ46_RS08975 (IUJ46_08930)	-	1739221..1739529 (+)	309	WP_010921804.1	hypothetical protein	-
IUJ46_RS08980 (IUJ46_08935)	proC	1739612..1740382 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=501097 IUJ46_RS08955 WP_010921800.1 1735984..1736418(+) (comYF) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=501097 IUJ46_RS08955 WP_010921800.1 1735984..1736418(+) (comYF) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389