Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | IMX21_RS17555 | Genome accession | NZ_CP064167 |
| Coordinates | 3602559..3603683 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228544.1 | Uniprot ID | A0A9P2PX49 |
| Organism | Escherichia coli O157:H7 strain Wll001 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 3576673..3603683 | 3602559..3603683 | within | 0 |
Gene organization within MGE regions
Location: 3576673..3603683
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IMX21_RS17340 (IMX21_17340) | rpsL | 3576673..3577047 (+) | 375 | WP_000246815.1 | 30S ribosomal protein S12 | - |
| IMX21_RS17345 (IMX21_17345) | rpsG | 3577144..3577614 (+) | 471 | WP_001138043.1 | 30S ribosomal protein S7 | - |
| IMX21_RS17350 (IMX21_17350) | fusA | 3577711..3579825 (+) | 2115 | WP_000124700.1 | elongation factor G | - |
| IMX21_RS17355 (IMX21_17355) | tuf | 3579896..3581080 (+) | 1185 | WP_000031783.1 | elongation factor Tu | - |
| IMX21_RS17360 (IMX21_17360) | bfd | 3581263..3581457 (+) | 195 | WP_000289090.1 | bacterioferritin-associated ferredoxin | - |
| IMX21_RS17365 (IMX21_17365) | bfr | 3581530..3582006 (+) | 477 | WP_000675516.1 | bacterioferritin | - |
| IMX21_RS17370 (IMX21_17370) | - | 3582003..3582470 (-) | 468 | WP_000381746.1 | A24 family peptidase | - |
| IMX21_RS17375 (IMX21_17375) | rpsJ | 3582849..3583160 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| IMX21_RS17380 (IMX21_17380) | rplC | 3583193..3583822 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| IMX21_RS17385 (IMX21_17385) | rplD | 3583833..3584438 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| IMX21_RS17390 (IMX21_17390) | rplW | 3584435..3584737 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| IMX21_RS17395 (IMX21_17395) | rplB | 3584755..3585576 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| IMX21_RS17400 (IMX21_17400) | rpsS | 3585593..3585871 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| IMX21_RS17405 (IMX21_17405) | rplV | 3585886..3586218 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| IMX21_RS17410 (IMX21_17410) | rpsC | 3586236..3586937 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| IMX21_RS17415 (IMX21_17415) | rplP | 3586950..3587360 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| IMX21_RS17420 (IMX21_17420) | rpmC | 3587360..3587551 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| IMX21_RS17425 (IMX21_17425) | rpsQ | 3587551..3587805 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| IMX21_RS17430 (IMX21_17430) | rplN | 3587970..3588341 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| IMX21_RS17435 (IMX21_17435) | rplX | 3588352..3588666 (+) | 315 | WP_000729185.1 | 50S ribosomal protein L24 | - |
| IMX21_RS17440 (IMX21_17440) | rplE | 3588681..3589220 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| IMX21_RS17445 (IMX21_17445) | rpsN | 3589235..3589540 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| IMX21_RS17450 (IMX21_17450) | rpsH | 3589574..3589966 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| IMX21_RS17455 (IMX21_17455) | rplF | 3589979..3590512 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| IMX21_RS17460 (IMX21_17460) | rplR | 3590522..3590875 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| IMX21_RS17465 (IMX21_17465) | rpsE | 3590890..3591393 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| IMX21_RS17470 (IMX21_17470) | rpmD | 3591397..3591576 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| IMX21_RS17475 (IMX21_17475) | rplO | 3591580..3592014 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| IMX21_RS17480 (IMX21_17480) | secY | 3592022..3593353 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| IMX21_RS17485 (IMX21_17485) | rpmJ | 3593385..3593501 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| IMX21_RS17490 (IMX21_17490) | rpsM | 3593648..3594004 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| IMX21_RS17495 (IMX21_17495) | rpsK | 3594021..3594410 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| IMX21_RS17500 (IMX21_17500) | rpsD | 3594444..3595064 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| IMX21_RS17505 (IMX21_17505) | rpoA | 3595090..3596079 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| IMX21_RS17510 (IMX21_17510) | rplQ | 3596120..3596503 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| IMX21_RS17515 (IMX21_17515) | yhdN | 3596610..3596978 (+) | 369 | WP_000266488.1 | DUF1992 domain-containing protein | - |
| IMX21_RS17520 (IMX21_17520) | zntR | 3596989..3597414 (+) | 426 | WP_000285607.1 | Zn(2+)-responsive transcriptional regulator | - |
| IMX21_RS17525 (IMX21_17525) | arfA | 3597470..3597688 (+) | 219 | WP_000092696.1 | alternative ribosome-rescue factor ArfA | - |
| IMX21_RS17530 (IMX21_17530) | mscL | 3597685..3598095 (-) | 411 | WP_000022442.1 | large-conductance mechanosensitive channel protein MscL | - |
| IMX21_RS17535 (IMX21_17535) | trkA | 3598225..3599601 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| IMX21_RS17540 (IMX21_17540) | rsmB | 3599623..3600912 (-) | 1290 | WP_001301795.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| IMX21_RS17545 (IMX21_17545) | fmt | 3600958..3601905 (-) | 948 | WP_000004459.1 | methionyl-tRNA formyltransferase | - |
| IMX21_RS17550 (IMX21_17550) | def | 3601920..3602429 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| IMX21_RS17555 (IMX21_17555) | dprA | 3602559..3603683 (+) | 1125 | WP_000228544.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 41005.96 Da Isoelectric Point: 6.2655
>NTDB_id=499911 IMX21_RS17555 WP_000228544.1 3602559..3603683(+) (dprA) [Escherichia coli O157:H7 strain Wll001]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=499911 IMX21_RS17555 WP_000228544.1 3602559..3603683(+) (dprA) [Escherichia coli O157:H7 strain Wll001]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Glaesserella parasuis strain SC1401 |
45.401 |
90.107 |
0.409 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.545 |
88.235 |
0.393 |