Detailed information NTG0499403

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: IRJ27_RS12910
• Genome accession: NZ_CP064095
• Coordinates: 2528439..2529596 (+)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain N1303-2Ay
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2523439..2534596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRJ27_RS12890	tuaH	2523907..2525100 (+)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-
IRJ27_RS12895	tagO	2525245..2526321 (+)	1077	WP_003227975.1	MraY family glycosyltransferase	-
IRJ27_RS12900	tagV	2526394..2527569 (-)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
IRJ27_RS12905	yvyE	2527569..2528222 (-)	654	WP_003227979.1	YigZ family protein	-
IRJ27_RS12910	degS	2528439..2529596 (+)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
IRJ27_RS12915	degU	2529679..2530368 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
IRJ27_RS12920	fakBA	2530466..2531311 (+)	846	WP_003244125.1	DegV family protein	-
IRJ27_RS12925	comFA	2531417..2532808 (+)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
IRJ27_RS12930	comFB	2532868..2533164 (+)	297	WP_003227989.1	late competence protein ComFB	-
IRJ27_RS12935	comFC	2533128..2533850 (+)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
IRJ27_RS12940	yvyF	2533924..2534343 (+)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=499403 IRJ27_RS12910 WP_003227983.1 2528439..2529596(+) (degS) [Bacillus subtilis strain N1303-2Ay]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=499403 IRJ27_RS12910 WP_003227983.1 2528439..2529596(+) (degS) [Bacillus subtilis strain N1303-2Ay]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1