Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSUD9_RS02280 Genome accession   NC_017620
Coordinates   438657..439940 (+) Length   427 a.a.
NCBI ID   WP_014636816.1    Uniprot ID   -
Organism   Streptococcus suis D9     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 433657..444940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD9_RS02255 (SSUD9_0451) - 434439..435080 (+) 642 WP_002937025.1 response regulator transcription factor -
  SSUD9_RS02260 (SSUD9_0452) - 435130..436530 (+) 1401 WP_002937018.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSUD9_RS02265 (SSUD9_0453) - 436532..436903 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  SSUD9_RS02270 (SSUD9_0454) cysK 436930..437856 (-) 927 WP_002937015.1 cysteine synthase A -
  SSUD9_RS02275 (SSUD9_0455) - 437946..438578 (-) 633 WP_004194123.1 YigZ family protein -
  SSUD9_RS02280 (SSUD9_0456) comFA/cflA 438657..439940 (+) 1284 WP_014636816.1 DEAD/DEAH box helicase Machinery gene
  SSUD9_RS02285 (SSUD9_0457) comFC/cflB 439933..440598 (+) 666 WP_004194119.1 ComF family protein Machinery gene
  SSUD9_RS02290 (SSUD9_0458) hpf 440675..441217 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 427 a.a.        Molecular weight: 48498.00 Da        Isoelectric Point: 9.2794

>NTDB_id=49727 SSUD9_RS02280 WP_014636816.1 438657..439940(+) (comFA/cflA) [Streptococcus suis D9]
MENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFKEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDFPIT
KCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQNDFS
VPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAADNAVKEAGVQVFLTATSTDELDKK
VRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKKTFP
EETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSIERPTGLLQ
FYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1284 bp        

>NTDB_id=49727 SSUD9_RS02280 WP_014636816.1 438657..439940(+) (comFA/cflA) [Streptococcus suis D9]
ATGGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAAAGTGCCAAG
TATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTAAAGAAGAAAACAAATTGCCAAACGATGCTTATTACT
GTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTTCCAATCACT
AAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGTGGAAAATAA
TCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAGTGATTGATA
AAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAATGACTTTTCA
GTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACATCAGTTATT
AAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCATGCTCTATC
AAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTGGATAAAAAA
GTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCAAAAAGTCTG
GTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAACAGAGAAAGT
CGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAAACATTCCCA
GAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAGAGAAATCAC
AGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAGCTAATCATT
ACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGAAGGAGTATAGAACGTCCGACTGGTTTACTTCAG
TTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGCTGGTTATGT
CTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(286-390)

Type III restriction enzyme, res subunit (ResIII)

(88-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.371

99.766

0.672
  comFA/cflA Streptococcus pneumoniae Rx1

66.667

99.766

0.665
  comFA/cflA Streptococcus pneumoniae D39

66.667

99.766

0.665
  comFA/cflA Streptococcus pneumoniae R6

66.667

99.766

0.665
  comFA/cflA Streptococcus pneumoniae TIGR4

66.667

99.766

0.665
  comFA/cflA Streptococcus mitis SK321

66.197

99.766

0.66
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.974

0.504
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.384
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

97.19

0.365

Multiple sequence alignment