Detailed information NTG0496939

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: IRE31_RS09735
• Genome accession: NZ_CP063829
• Coordinates: 1884393..1884854 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 19A-ST320_99-176
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1879393..1889854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRE31_RS09700 (IRE31_09640)	-	1879704..1880528 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
IRE31_RS09705 (IRE31_09645)	rnpA	1880503..1880874 (-)	372	WP_000739246.1	ribonuclease P protein component	-
IRE31_RS09710	-	1880891..1881022 (-)	132	WP_000768904.1	hypothetical protein	-
IRE31_RS09715 (IRE31_09650)	-	1881023..1882213 (-)	1191	WP_000167766.1	acetate kinase	-
IRE31_RS09720 (IRE31_09655)	comYH	1882264..1883217 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
IRE31_RS09725 (IRE31_09660)	-	1883278..1883865 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
IRE31_RS09730 (IRE31_09665)	comGG/cglG	1884002..1884415 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
IRE31_RS09735 (IRE31_09670)	comGF/cglF	1884393..1884854 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
IRE31_RS09740 (IRE31_09675)	comGE/cglE	1884817..1885119 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
IRE31_RS09745 (IRE31_09680)	comGD/cglD	1885082..1885486 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
IRE31_RS09750 (IRE31_09685)	comGC/cglC	1885479..1885805 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
IRE31_RS09755 (IRE31_09690)	comGB/cglB	1885807..1886823 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
IRE31_RS09760 (IRE31_09695)	comGA/cglA/cilD	1886771..1887712 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
IRE31_RS09765 (IRE31_09700)	-	1887788..1888153 (-)	366	WP_000286415.1	DUF1033 family protein	-
IRE31_RS09770 (IRE31_09705)	-	1888304..1889362 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=496939 IRE31_RS09735 WP_000250545.1 1884393..1884854(-) (comGF/cglF) [Streptococcus pneumoniae strain 19A-ST320_99-176]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=496939 IRE31_RS09735 WP_000250545.1 1884393..1884854(-) (comGF/cglF) [Streptococcus pneumoniae strain 19A-ST320_99-176]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915