NTDB

Overview

Name	comGE/cglE	Type	Machinery gene
Locus tag	IRE31_RS09740	Genome accession	NZ_CP063829
Coordinates	1884817..1885119 (-)	Length	100 a.a.
NCBI ID	WP_000413380.1	Uniprot ID	-
Organism	Streptococcus pneumoniae strain 19A-ST320_99-176
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1879817..1890119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IRE31_RS09705 (IRE31_09645)	rnpA	1880503..1880874 (-)	372	WP_000739246.1	ribonuclease P protein component	-
IRE31_RS09710	-	1880891..1881022 (-)	132	WP_000768904.1	hypothetical protein	-
IRE31_RS09715 (IRE31_09650)	-	1881023..1882213 (-)	1191	WP_000167766.1	acetate kinase	-
IRE31_RS09720 (IRE31_09655)	comYH	1882264..1883217 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
IRE31_RS09725 (IRE31_09660)	-	1883278..1883865 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
IRE31_RS09730 (IRE31_09665)	comGG/cglG	1884002..1884415 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
IRE31_RS09735 (IRE31_09670)	comGF/cglF	1884393..1884854 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
IRE31_RS09740 (IRE31_09675)	comGE/cglE	1884817..1885119 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
IRE31_RS09745 (IRE31_09680)	comGD/cglD	1885082..1885486 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
IRE31_RS09750 (IRE31_09685)	comGC/cglC	1885479..1885805 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
IRE31_RS09755 (IRE31_09690)	comGB/cglB	1885807..1886823 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
IRE31_RS09760 (IRE31_09695)	comGA/cglA/cilD	1886771..1887712 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
IRE31_RS09765 (IRE31_09700)	-	1887788..1888153 (-)	366	WP_000286415.1	DUF1033 family protein	-
IRE31_RS09770 (IRE31_09705)	-	1888304..1889362 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

Download Length: 100 a.a. Molecular weight: 11135.11 Da Isoelectric Point: 9.7273

                                >NTDB_id=496940 IRE31_RS09740 WP_000413380.1 1884817..1885119(-) (comGE/cglE) [Streptococcus pneumoniae strain 19A-ST320_99-176]

MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS

SEKGLEVYHGSEQLLAIKEP

Nucleotide

Download Length: 303 bp

                                >NTDB_id=496940 IRE31_RS09740 WP_000413380.1 1884817..1885119(-) (comGE/cglE) [Streptococcus pneumoniae strain 19A-ST320_99-176]

ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT

TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG

TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT

AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGE/cglE	Streptococcus mitis NCTC 12261	99	100	0.99
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	43.333	90	0.39
comYE	Streptococcus mutans UA159	43.333	90	0.39

Detailed information NTG0496940