Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   IM712_RS17970 Genome accession   NZ_CP063768
Coordinates   3695493..3696149 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain KMU01     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3690493..3701149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM712_RS17950 spxH 3690732..3691634 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  IM712_RS17955 - 3691920..3692087 (+) 168 WP_003155026.1 hypothetical protein -
  IM712_RS17960 pepF 3692125..3693954 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  IM712_RS17965 - 3694182..3695342 (-) 1161 WP_077722056.1 competence protein CoiA family protein -
  IM712_RS17970 mecA 3695493..3696149 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  IM712_RS17975 - 3696132..3696242 (-) 111 Protein_3517 adaptor protein MecA -
  IM712_RS17980 - 3696425..3697081 (+) 657 WP_003155033.1 TerC family protein -
  IM712_RS17985 spx 3697139..3697534 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  IM712_RS17990 - 3697713..3698291 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  IM712_RS17995 - 3698409..3699596 (-) 1188 WP_077722055.1 putative glycoside hydrolase -
  IM712_RS18000 oppF 3699703..3700620 (-) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=496630 IM712_RS17970 WP_003155032.1 3695493..3696149(-) (mecA) [Bacillus velezensis strain KMU01]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=496630 IM712_RS17970 WP_003155032.1 3695493..3696149(-) (mecA) [Bacillus velezensis strain KMU01]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895