Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SSGZ1_RS04960 Genome accession   NC_017617
Coordinates   1008740..1010119 (-) Length   459 a.a.
NCBI ID   WP_014635993.1    Uniprot ID   -
Organism   Streptococcus suis GZ1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1003740..1015119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSGZ1_RS04935 (SSGZ1_0957) - 1003949..1005225 (-) 1277 Protein_926 pyrimidine-nucleoside phosphorylase -
  SSGZ1_RS04940 (SSGZ1_0958) - 1005222..1005812 (-) 591 WP_014635990.1 class I SAM-dependent methyltransferase -
  SSGZ1_RS04945 (SSGZ1_0959) coaA 1005921..1006841 (+) 921 WP_002935283.1 type I pantothenate kinase -
  SSGZ1_RS04950 (SSGZ1_0960) rpsT 1006900..1007148 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  SSGZ1_RS04955 (SSGZ1_0961) - 1007411..1008640 (-) 1230 WP_024389538.1 transglutaminase domain-containing protein -
  SSGZ1_RS04960 (SSGZ1_0962) ciaH 1008740..1010119 (-) 1380 WP_014635993.1 sensor histidine kinase Regulator
  SSGZ1_RS04965 (SSGZ1_0963) ciaR 1010112..1010783 (-) 672 WP_014637852.1 response regulator transcription factor Regulator
  SSGZ1_RS04970 (SSGZ1_0964) - 1010977..1011324 (-) 348 WP_014635995.1 hypothetical protein -
  SSGZ1_RS04975 (SSGZ1_0965) phoU 1011490..1012146 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  SSGZ1_RS04980 (SSGZ1_0966) pstB 1012175..1012933 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  SSGZ1_RS04985 (SSGZ1_0967) pstB 1012945..1013748 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  SSGZ1_RS04990 (SSGZ1_0968) pstA 1013773..1014660 (-) 888 WP_014635996.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51926.60 Da        Isoelectric Point: 6.8975

>NTDB_id=49583 SSGZ1_RS04960 WP_014635993.1 1008740..1010119(-) (ciaH) [Streptococcus suis GZ1]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKEAMVESSFGM
SEDYRYVTIELPTDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDT
DRKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=49583 SSGZ1_RS04960 WP_014635993.1 1008740..1010119(-) (ciaH) [Streptococcus suis GZ1]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAATGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGCCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCAAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACTGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATACC
GATAGGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

48.922

100

0.495
  ciaH Streptococcus pneumoniae D39

48.922

100

0.495
  ciaH Streptococcus pneumoniae R6

48.922

100

0.495
  ciaH Streptococcus pneumoniae TIGR4

48.922

100

0.495
  ciaH Streptococcus mutans UA159

49.888

97.386

0.486

Multiple sequence alignment