Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IOD66_RS09310 Genome accession   NZ_CP063424
Coordinates   1990145..1991299 (-) Length   384 a.a.
NCBI ID   WP_009875464.1    Uniprot ID   A3N310
Organism   Actinobacillus pleuropneumoniae strain APP5     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1985145..1996299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IOD66_RS09290 (IOD66_09305) secE 1985521..1985934 (-) 414 WP_005602526.1 preprotein translocase subunit SecE -
  IOD66_RS09295 (IOD66_09310) - 1986237..1986509 (+) 273 WP_005599206.1 PTS sugar transporter subunit IIB -
  IOD66_RS09300 (IOD66_09315) - 1986518..1987873 (+) 1356 WP_247797585.1 PTS ascorbate transporter subunit IIC -
  IOD66_RS09305 (IOD66_09320) - 1988095..1990101 (+) 2007 WP_011848643.1 oligopeptide transporter, OPT family -
  IOD66_RS09310 (IOD66_09325) dprA 1990145..1991299 (-) 1155 WP_009875464.1 DNA-processing protein DprA Machinery gene
  IOD66_RS09315 (IOD66_09330) def 1991485..1991997 (+) 513 WP_005599196.1 peptide deformylase -
  IOD66_RS09320 (IOD66_09335) rfaD 1992137..1993063 (+) 927 WP_005599195.1 ADP-glyceromanno-heptose 6-epimerase -
  IOD66_RS09325 (IOD66_09340) - 1993123..1994365 (-) 1243 Protein_1793 surface lipoprotein assembly modifier -
  IOD66_RS09330 (IOD66_09345) - 1994668..1995102 (-) 435 WP_009875461.1 factor H binding protein domain-containing protein -
  IOD66_RS09335 (IOD66_09350) - 1995136..1995324 (+) 189 WP_005599189.1 hypothetical protein -
  IOD66_RS09340 (IOD66_09355) - 1995448..1996185 (-) 738 WP_247797586.1 hypothetical protein -

Sequence

Protein


Download         Length: 384 a.a.        Molecular weight: 42831.05 Da        Isoelectric Point: 5.4205

>NTDB_id=495573 IOD66_RS09310 WP_009875464.1 1990145..1991299(-) (dprA) [Actinobacillus pleuropneumoniae strain APP5]
MSQADLLKLLQIPQLGAQRIARLLSEVDFAQFCQYDKRQLQQIGWNEKQIQRWFNPEMRWIDNALTWAERPNQHLLSLFD
EEYPFLLRQISTAPPVLFVRGSLSSLSLPQIAIVGSRDFSAYGEYWAGYFSEQLVKHHLAVTSGLAIGIDGFCHQRAVAE
QGITIAVLGSGLDQVYPARHKKLAEQIVESGGALVSEFFPNQPPLAENFPRRNRIISGLSLGTLVVEATLNSGSLITARY
ALEQGREVFALPNSVQNPYAQGCHKLIKEGAVLTETIEDILQAIQYQLPDQPWQQALFEPPQAVENAQFFTKADVPNKVN
HLAKKLPELTACQQQIVAHISLEPISIDDLAKATSLEVETLLVELLGLELLSVIKQVSGGYVRQ

Nucleotide


Download         Length: 1155 bp        

>NTDB_id=495573 IOD66_RS09310 WP_009875464.1 1990145..1991299(-) (dprA) [Actinobacillus pleuropneumoniae strain APP5]
ATGTCTCAGGCTGATTTACTGAAATTATTGCAGATTCCGCAACTGGGGGCGCAGCGCATTGCTCGTCTGTTATCCGAAGT
GGATTTTGCCCAATTTTGCCAATATGACAAACGCCAATTACAACAAATTGGTTGGAACGAGAAACAGATTCAACGCTGGT
TCAATCCGGAAATGCGTTGGATTGATAATGCTCTCACGTGGGCGGAGCGGCCGAATCAACACTTATTGAGCTTATTTGAT
GAGGAATATCCGTTTTTATTACGGCAAATCAGCACCGCACCGCCGGTGTTATTTGTGCGAGGTTCGCTAAGCAGTTTGAG
CTTGCCGCAAATTGCGATTGTCGGTAGTCGAGACTTTTCCGCCTACGGAGAATACTGGGCGGGCTATTTTAGCGAGCAAT
TGGTTAAACATCATTTGGCGGTTACTAGCGGACTTGCAATCGGCATAGACGGTTTTTGCCATCAGCGAGCGGTAGCGGAA
CAGGGTATTACGATTGCTGTGTTGGGCAGCGGTTTAGATCAAGTCTATCCGGCAAGGCACAAAAAATTGGCGGAGCAAAT
TGTCGAAAGCGGCGGGGCGTTAGTGTCGGAATTTTTTCCGAATCAACCGCCGCTTGCCGAAAATTTCCCTCGTCGTAATC
GCATTATCAGCGGTTTGTCACTCGGTACGTTAGTGGTGGAAGCCACATTAAATAGCGGTTCGCTGATTACCGCCCGTTAT
GCGTTGGAACAAGGGCGAGAAGTGTTTGCATTACCGAATTCGGTACAAAATCCGTATGCACAAGGCTGTCATAAACTGAT
CAAAGAAGGGGCGGTTTTAACCGAAACGATAGAGGATATTTTACAGGCAATTCAATATCAACTGCCGGATCAGCCTTGGC
AACAGGCTCTGTTTGAACCGCCACAAGCGGTTGAAAACGCACAATTTTTTACAAAAGCAGATGTGCCGAATAAGGTCAAT
CATCTTGCAAAAAAATTGCCGGAATTGACCGCTTGTCAGCAACAAATTGTGGCGCATATTAGTCTTGAACCGATTTCGAT
TGACGATTTGGCTAAGGCGACTTCATTGGAGGTGGAAACACTGTTAGTCGAGTTACTGGGTTTGGAATTATTAAGTGTGA
TTAAGCAGGTAAGCGGCGGTTATGTCAGACAATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-274)

DprA winged helix domain (DprA_WH)

(325-380)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N310

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

75.198

98.698

0.742
  dprA Vibrio campbellii strain DS40M4

46.719

99.219

0.464
  dprA Haemophilus influenzae Rd KW20

49.28

90.365

0.445
  dprA Vibrio cholerae strain A1552

41.86

100

0.422
  dprA Legionella pneumophila strain ERS1305867

37.598

99.74

0.375