Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SSAL_RS04210 Genome accession   NC_017594
Coordinates   942744..944159 (+) Length   471 a.a.
NCBI ID   WP_045001673.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 937744..949159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS04185 (Ssal_00938) - 938195..938767 (-) 573 WP_004182105.1 ECF transporter S component -
  SSAL_RS04190 (Ssal_00939) coaC 938796..939341 (-) 546 WP_014633033.1 phosphopantothenoylcysteine decarboxylase -
  SSAL_RS04195 (Ssal_00940) - 939334..940017 (-) 684 WP_014633034.1 phosphopantothenate--cysteine ligase -
  SSAL_RS04200 (Ssal_00941) - 940211..941881 (+) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  SSAL_RS04205 (Ssal_00942) ciaR 942080..942754 (+) 675 WP_004182019.1 response regulator transcription factor Regulator
  SSAL_RS04210 (Ssal_00943) ciaH 942744..944159 (+) 1416 WP_045001673.1 HAMP domain-containing sensor histidine kinase Regulator
  SSAL_RS04215 (Ssal_00944) rpsT 944243..944479 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  SSAL_RS04220 (Ssal_00945) coaA 944549..945469 (-) 921 WP_014633037.1 type I pantothenate kinase -
  SSAL_RS04225 (Ssal_00946) - 945582..946172 (+) 591 WP_014633038.1 class I SAM-dependent methyltransferase -
  SSAL_RS04230 (Ssal_00947) - 946169..947458 (+) 1290 WP_014633039.1 pyrimidine-nucleoside phosphorylase -
  SSAL_RS04235 (Ssal_00948) deoC 947480..948142 (+) 663 WP_004182396.1 deoxyribose-phosphate aldolase -
  SSAL_RS04240 (Ssal_00949) - 948129..948527 (+) 399 WP_004182397.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53485.24 Da        Isoelectric Point: 8.7640

>NTDB_id=49400 SSAL_RS04210 WP_045001673.1 942744..944159(+) (ciaH) [Streptococcus salivarius 57.I]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRSIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRQLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=49400 SSAL_RS04210 WP_045001673.1 942744..944159(+) (ciaH) [Streptococcus salivarius 57.I]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTTTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTTTGAGTTACGGCGTTTATTCCAATGTGGATTCTA
GTCTGAAAATGGCAGCGACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCAACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TGGTACTTGATAAGAATGGGAAAGTCCTCAATGTCGTTGATAAATTTTCAAGTTTATCTAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACAGAAAAGTATCGTCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCACTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAATTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTAGTCGTTCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCAACTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment