Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP89_RS08770 Genome accession   NZ_CP063127
Coordinates   1760818..1762038 (+) Length   406 a.a.
NCBI ID   WP_012054946.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M1C112_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1755818..1767038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP89_RS08750 (INP89_08745) corC 1756781..1757680 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  INP89_RS08755 (INP89_08750) ampD 1758303..1758866 (-) 564 WP_012054949.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP89_RS08760 (INP89_08755) pilA 1758981..1759430 (+) 450 WP_012054948.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  INP89_RS08765 (INP89_08760) pilB 1759427..1760821 (+) 1395 WP_012054947.1 GspE/PulE family protein Machinery gene
  INP89_RS08770 (INP89_08765) pilC 1760818..1762038 (+) 1221 WP_012054946.1 type II secretion system F family protein Machinery gene
  INP89_RS08775 (INP89_08770) pilD 1762035..1762727 (+) 693 WP_005666688.1 prepilin peptidase Machinery gene
  INP89_RS08780 (INP89_08775) rho 1762782..1764044 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  INP89_RS08785 (INP89_08780) metJ 1764292..1764609 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  INP89_RS08790 (INP89_08785) cueR 1764623..1765009 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  INP89_RS08795 (INP89_08790) - 1765086..1765292 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  INP89_RS08800 (INP89_08795) - 1765366..1765572 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  INP89_RS08805 (INP89_08800) - 1765658..1765864 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  INP89_RS08810 (INP89_08805) - 1765950..1766156 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46340.55 Da        Isoelectric Point: 9.6409

>NTDB_id=493249 INP89_RS08770 WP_012054946.1 1760818..1762038(+) (pilC) [Haemophilus influenzae strain M1C112_1]
MTKKLFYYQASNALNQEQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQEKYLTQQEIQLIQVGEMTGKLAIVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYNFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIVDNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=493249 INP89_RS08770 WP_012054946.1 1760818..1762038(+) (pilC) [Haemophilus influenzae strain M1C112_1]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGGAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTGCTTCAATCGATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGAGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCATAGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATAACTTCTATCTAAAACGCCAAACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGTGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.537

100

0.975
  pilC Glaesserella parasuis strain SC1401

37.656

98.768

0.372