Detailed information NTG0493222

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: INP89_RS05125
• Genome accession: NZ_CP063127
• Coordinates: 1044183..1045304 (+)
• Length: 373 a.a.
• NCBI ID: WP_012055334.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain M1C112_1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1039183..1050304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP89_RS05110 (INP89_05105)	leuC	1039327..1040736 (-)	1410	WP_074039315.1	3-isopropylmalate dehydratase large subunit	-
INP89_RS05115 (INP89_05110)	leuB	1040912..1041991 (-)	1080	WP_074039317.1	3-isopropylmalate dehydrogenase	-
INP89_RS05120 (INP89_05115)	leuA	1042078..1043625 (-)	1548	WP_074039319.1	2-isopropylmalate synthase	-
INP89_RS05125 (INP89_05120)	dprA	1044183..1045304 (+)	1122	WP_012055334.1	DNA-processing protein DprA	Machinery gene
INP89_RS05130 (INP89_05125)	yaaA	1045357..1046133 (+)	777	WP_012055333.1	peroxide stress protein YaaA	-
INP89_RS05135 (INP89_05130)	-	1046126..1046707 (+)	582	WP_005651586.1	hypothetical protein	-
INP89_RS05140 (INP89_05135)	pfkA	1046803..1047768 (+)	966	WP_005659252.1	6-phosphofructokinase	-
INP89_RS05145 (INP89_05140)	smpB	1048007..1048492 (+)	486	WP_005659251.1	SsrA-binding protein SmpB	-
INP89_RS05150 (INP89_05145)	fis	1048587..1048886 (-)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
INP89_RS05155 (INP89_05150)	dusB	1048880..1049860 (-)	981	WP_012055332.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41639.71 Da
• Isoelectric Point: 6.4124

>NTDB_id=493222 INP89_RS05125 WP_012055334.1 1044183..1045304(+) (dprA) [Haemophilus influenzae strain M1C112_1]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=493222 INP89_RS05125 WP_012055334.1 1044183..1045304(+) (dprA) [Haemophilus influenzae strain M1C112_1]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTCGCGTGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAAACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAGGCTGTCGTT
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAATTTTTACCAAACCAAGCACCTATTGCTGCTAATTTTCCACGCC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGTGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTGATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGACATTTTGGAAACGCTCTACCAACATTCTATCCACAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCCGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTACTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCGGAAGAATTTAACTTGAGTGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.196	100	0.992
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.617	100	0.44
dprA	Vibrio cholerae strain A1552	43.014	97.855	0.421
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378