Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP92_RS00265 Genome accession   NZ_CP063122
Coordinates   55138..56361 (+) Length   407 a.a.
NCBI ID   WP_197554240.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C125_4     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 50138..61361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP92_RS00240 (INP92_00240) - 50723..51517 (-) 795 WP_197554234.1 sulfite exporter TauE/SafE family protein -
  INP92_RS00245 (INP92_00245) rppH 51517..52110 (-) 594 WP_197554237.1 RNA pyrophosphohydrolase -
  INP92_RS00250 (INP92_00250) ampD 52594..53157 (-) 564 WP_197544811.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP92_RS00255 (INP92_00255) pilA 53300..53743 (+) 444 WP_197544812.1 prepilin peptidase-dependent pilin Machinery gene
  INP92_RS00260 (INP92_00260) pilB 53750..55129 (+) 1380 WP_197544813.1 GspE/PulE family protein Machinery gene
  INP92_RS00265 (INP92_00265) pilC 55138..56361 (+) 1224 WP_197554240.1 type II secretion system F family protein Machinery gene
  INP92_RS00270 (INP92_00270) pilD 56358..57035 (+) 678 WP_197544815.1 prepilin peptidase Machinery gene
  INP92_RS00275 (INP92_00275) coaE 57124..57744 (+) 621 WP_197544816.1 dephospho-CoA kinase -
  INP92_RS00280 (INP92_00280) yacG 57737..57943 (+) 207 WP_197544817.1 DNA gyrase inhibitor YacG -
  INP92_RS00285 (INP92_00285) - 57940..58221 (+) 282 WP_197544818.1 GNAT family N-acetyltransferase -
  INP92_RS00290 (INP92_00290) rhlB 58312..59574 (+) 1263 WP_197544819.1 ATP-dependent RNA helicase RhlB -
  INP92_RS00295 (INP92_00295) mreD 59616..60104 (-) 489 WP_193451403.1 rod shape-determining protein MreD -
  INP92_RS00300 (INP92_00300) mreC 60104..61168 (-) 1065 WP_197544820.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46302.97 Da        Isoelectric Point: 9.6100

>NTDB_id=493127 INP92_RS00265 WP_197554240.1 55138..56361(+) (pilC) [Haemophilus parainfluenzae strain M1C125_4]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFQLIAKGFNHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCSQLGLHEWLGALIELIESGLPFSQSLEMQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPILTAVLLAMSQFLQHHFIALMIVCIFALFMLKMALKHSLW
LNQKKNALISRMPIWGNIICLSRLISFSHNLQLMLQSGVALMPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=493127 INP92_RS00265 WP_197554240.1 55138..56361(+) (pilC) [Haemophilus parainfluenzae strain M1C125_4]
ATGGCAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGTCTTGTTGCCCAATC
TAAACAAGCTGCACAATTCCAGTTAATCGCAAAAGGTTTTAATCACATTCGCTTACAACAAGATTGGCAACTTAATCAGA
AACCGAAAAATGCAGAAATCAGTGCTTTATTGAATCAACTGGCTACATTACTCAGTTCAGCCATTCCATTAAAGAATGCA
TTACATATTTTGCAAGATAACTGCTCGCAATTGGGATTGCATGAGTGGCTTGGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGTTTGGAAATGCAAGGAAAGTATTTAAATTTTCAAGAAATTCAACTTATTCAAGTGGGAGAAA
TGACCGGAAAACTGGCGGAGGTATGCACTAAAATTGCAGAACGTCGAACACAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCTGCCATGGTATTAGGTATTTCGCTTTCACTTACGTTGATTTTATTACTCTTTGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAACTCAGCTGAGCTACCTATATTGACTGCCGTATTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTATCGCCTTGATGATTGTCTGCATTTTCGCTCTTTTTATGCTAAAGATGGCATTAAAACATTCTCTTTGG
CTAAATCAAAAAAAGAATGCGCTGATTAGTCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGTCTAATCAGTTT
TAGTCATAACTTACAATTAATGCTTCAATCCGGTGTAGCATTAATGCCTGCGCTAAATAGTTTTCTCCCCAAACAACAAA
CCTGGCAAACACAACGTACCTTAAAAGGCGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGTGTCAGTAGTCATCTTTTCCCAATGGAAGCACAACAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCGTTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAACTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATTGGTATTATTATGATGGGCATGTATCTGCCGATTTTT
AATATGGGATCGGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.802

99.263

0.693
  pilC Haemophilus influenzae 86-028NP

68.812

99.263

0.683
  pilC Glaesserella parasuis strain SC1401

39.651

98.526

0.391