Detailed information NTG0493112

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: INP93_RS04485
• Genome accession: NZ_CP063121
• Coordinates: 910073..911191 (+)
• Length: 372 a.a.
• NCBI ID: WP_197544194.1
• Uniprot ID: A0A7M1NZQ4
• Organism: Haemophilus parainfluenzae strain M1C130_2
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 905073..916191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP93_RS04470 (INP93_04470)	-	906395..906688 (-)	294	WP_049373133.1	YciI family protein	-
INP93_RS04475 (INP93_04475)	leuB	906767..907843 (-)	1077	WP_197545252.1	3-isopropylmalate dehydrogenase	-
INP93_RS04480 (INP93_04480)	leuA	908003..909550 (-)	1548	WP_005696823.1	2-isopropylmalate synthase	-
INP93_RS04485 (INP93_04485)	dprA	910073..911191 (+)	1119	WP_197544194.1	DNA-processing protein DprA	Machinery gene
INP93_RS04490 (INP93_04490)	yaaA	911256..912032 (+)	777	WP_049375008.1	peroxide stress protein YaaA	-
INP93_RS04495 (INP93_04495)	-	912025..912615 (+)	591	WP_197544195.1	hypothetical protein	-
INP93_RS04500 (INP93_04500)	pfkA	912728..913693 (+)	966	WP_070591696.1	6-phosphofructokinase	-
INP93_RS04505 (INP93_04505)	uhpC	913771..915096 (-)	1326	WP_197545253.1	MFS transporter family glucose-6-phosphate receptor UhpC	-
INP93_RS04510 (INP93_04510)	folA	915300..915785 (-)	486	WP_197545254.1	type 3 dihydrofolate reductase	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41413.66 Da
• Isoelectric Point: 5.7277

>NTDB_id=493112 INP93_RS04485 WP_197544194.1 910073..911191(+) (dprA) [Haemophilus parainfluenzae strain M1C130_2]
MSDFTSILLRLAQVPKLGSVRIQQILAHVNIEELLNYDEVAFQQMGWEALQIRRWFQPEMKFIEPALSWAEKEGHHLIHC
FSDDYPFLLKQISGFPPLLFVKGNLIALSAQQIAMVGSRYCSAYGEYWAKYFATELSLAGLTVTSGLAVGIDGFSHQAVV
DIQGQTIAVLGSGLDHIYPAKHRRLAEQIIENNGALVSEFIPTQAPIAENFPRRNRIISGLSLGTLVIEATEKSGSLITA
RYALEQNRDIFALPGNIQSEYSQGCHKLIKQGAMLVENVKDILDSLNHSVVFQPPVHNTQINKPIAQPLTAKTLAVEPSH
PELYQHISYTPISLDDLSVTLNLPVDLLLVQLLDLELQDLIVNENGLYKRIA

Nucleotide

• Length: 1119 bp

>NTDB_id=493112 INP93_RS04485 WP_197544194.1 910073..911191(+) (dprA) [Haemophilus parainfluenzae strain M1C130_2]
ATGAGCGATTTTACGTCGATTTTGTTGCGATTAGCTCAAGTGCCCAAATTGGGCAGTGTGCGGATTCAACAAATTTTGGC
CCATGTGAATATAGAAGAATTGTTAAATTATGATGAAGTGGCATTTCAACAAATGGGTTGGGAGGCTTTGCAGATTCGTC
GTTGGTTTCAGCCAGAAATGAAATTTATTGAACCCGCTTTGAGCTGGGCAGAAAAAGAAGGCCATCATTTAATACACTGT
TTTTCAGATGACTATCCTTTTTTACTCAAACAAATTAGTGGCTTTCCGCCCTTATTATTTGTGAAAGGTAATCTGATCGC
ACTTTCAGCACAGCAAATCGCCATGGTTGGAAGTCGTTATTGCTCCGCTTATGGGGAATATTGGGCAAAATATTTTGCGA
CAGAGCTTTCTCTCGCAGGATTAACGGTGACGAGTGGGTTGGCTGTAGGTATCGATGGATTTAGCCATCAGGCGGTGGTG
GATATTCAAGGGCAGACCATTGCCGTATTGGGCAGCGGATTAGATCACATTTACCCCGCTAAACATCGCCGATTAGCCGA
GCAAATTATCGAAAATAACGGGGCATTAGTTTCTGAATTTATCCCTACGCAAGCACCGATTGCTGAAAATTTTCCTCGTC
GTAATCGCATTATTAGCGGGCTTTCATTAGGAACATTAGTCATTGAAGCCACAGAGAAAAGCGGTTCATTGATTACAGCA
CGCTATGCTTTAGAACAAAATCGCGATATTTTTGCCTTACCAGGGAATATTCAAAGTGAATACAGTCAAGGCTGCCATAA
ACTGATTAAGCAAGGGGCGATGTTGGTGGAAAATGTCAAAGATATTTTAGATAGCCTCAATCACAGCGTTGTTTTTCAGC
CTCCAGTACATAATACGCAAATTAATAAGCCGATAGCTCAACCACTCACAGCAAAAACACTAGCCGTGGAACCAAGTCAT
CCTGAACTTTATCAACATATCAGTTATACACCAATAAGCCTTGATGATTTATCGGTTACATTGAATTTGCCGGTGGATTT
GCTTTTAGTGCAGTTGTTAGATTTGGAGTTACAAGATTTAATCGTCAATGAGAATGGACTCTATAAGCGGATAGCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (70-277)

• DprA winged helix domain (DprA_WH) (311-363)

3D structure

• AlphaFold DB: A0A7M1NZQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	71.314	100	0.715
dprA	Glaesserella parasuis strain SC1401	57.267	92.473	0.53
dprA	Vibrio campbellii strain DS40M4	43.28	100	0.433
dprA	Vibrio cholerae strain A1552	42.818	99.194	0.425
dprA	Legionella pneumophila strain ERS1305867	40.27	99.462	0.401