Detailed information NTG0493081

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: INP94_RS04870
• Genome accession: NZ_CP063120
• Coordinates: 991245..992363 (+)
• Length: 372 a.a.
• NCBI ID: WP_197544194.1
• Uniprot ID: A0A7M1NZQ4
• Organism: Haemophilus parainfluenzae strain M1C137_2
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 986245..997363

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP94_RS04855 (INP94_04855)	leuC	986461..987870 (-)	1410	WP_041918225.1	3-isopropylmalate dehydratase large subunit	-
INP94_RS04860 (INP94_04860)	leuB	988025..989101 (-)	1077	WP_197544193.1	3-isopropylmalate dehydrogenase	-
INP94_RS04865 (INP94_04865)	leuA	989175..990722 (-)	1548	WP_005696823.1	2-isopropylmalate synthase	-
INP94_RS04870 (INP94_04870)	dprA	991245..992363 (+)	1119	WP_197544194.1	DNA-processing protein DprA	Machinery gene
INP94_RS04875 (INP94_04875)	yaaA	992428..993204 (+)	777	WP_049375008.1	peroxide stress protein YaaA	-
INP94_RS04880 (INP94_04880)	-	993197..993787 (+)	591	WP_197544195.1	hypothetical protein	-
INP94_RS04885 (INP94_04885)	pfkA	993900..994865 (+)	966	WP_049363272.1	6-phosphofructokinase	-
INP94_RS04890 (INP94_04890)	folA	994943..995443 (-)	501	WP_197544196.1	type 3 dihydrofolate reductase	-
INP94_RS04895 (INP94_04895)	proB	995585..996694 (+)	1110	WP_197544197.1	glutamate 5-kinase	-
INP94_RS04900 (INP94_04900)	-	996807..997187 (+)	381	WP_049365632.1	hypothetical protein	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41413.66 Da
• Isoelectric Point: 5.7277

>NTDB_id=493081 INP94_RS04870 WP_197544194.1 991245..992363(+) (dprA) [Haemophilus parainfluenzae strain M1C137_2]
MSDFTSILLRLAQVPKLGSVRIQQILAHVNIEELLNYDEVAFQQMGWEALQIRRWFQPEMKFIEPALSWAEKEGHHLIHC
FSDDYPFLLKQISGFPPLLFVKGNLIALSAQQIAMVGSRYCSAYGEYWAKYFATELSLAGLTVTSGLAVGIDGFSHQAVV
DIQGQTIAVLGSGLDHIYPAKHRRLAEQIIENNGALVSEFIPTQAPIAENFPRRNRIISGLSLGTLVIEATEKSGSLITA
RYALEQNRDIFALPGNIQSEYSQGCHKLIKQGAMLVENVKDILDSLNHSVVFQPPVHNTQINKPIAQPLTAKTLAVEPSH
PELYQHISYTPISLDDLSVTLNLPVDLLLVQLLDLELQDLIVNENGLYKRIA

Nucleotide

• Length: 1119 bp

>NTDB_id=493081 INP94_RS04870 WP_197544194.1 991245..992363(+) (dprA) [Haemophilus parainfluenzae strain M1C137_2]
ATGAGCGATTTTACGTCGATTTTGTTGCGATTAGCTCAAGTGCCCAAATTGGGCAGTGTGCGGATTCAACAAATTTTGGC
CCATGTGAATATAGAAGAATTGTTAAATTATGATGAAGTGGCATTTCAACAAATGGGTTGGGAGGCTTTGCAGATTCGTC
GTTGGTTTCAGCCAGAAATGAAATTTATTGAACCCGCTTTGAGCTGGGCAGAAAAAGAAGGCCATCATTTAATACACTGT
TTTTCAGATGACTATCCTTTTTTACTCAAACAAATTAGTGGCTTTCCGCCCTTATTATTTGTGAAAGGTAATCTGATCGC
ACTTTCAGCACAGCAAATCGCCATGGTTGGAAGTCGTTATTGCTCCGCTTATGGGGAATATTGGGCAAAATATTTTGCGA
CAGAGCTTTCTCTCGCAGGATTAACGGTGACGAGTGGGTTGGCTGTAGGTATCGATGGATTTAGCCATCAGGCGGTGGTG
GATATTCAAGGGCAGACCATTGCCGTATTGGGCAGCGGATTAGATCACATTTACCCCGCTAAACATCGCCGATTAGCCGA
GCAAATTATCGAAAATAACGGGGCATTAGTTTCTGAATTTATCCCTACGCAAGCACCGATTGCTGAAAATTTTCCTCGTC
GTAATCGCATTATTAGCGGGCTTTCATTAGGAACATTAGTCATTGAAGCCACAGAGAAAAGCGGTTCATTGATTACAGCA
CGCTATGCTTTAGAACAAAATCGCGATATTTTTGCCTTACCAGGGAATATTCAAAGTGAATACAGTCAAGGCTGCCATAA
ACTGATTAAGCAAGGGGCGATGTTGGTGGAAAATGTCAAAGATATTTTAGATAGCCTCAATCACAGCGTTGTTTTTCAGC
CTCCAGTACATAATACGCAAATTAATAAGCCGATAGCTCAACCACTCACAGCAAAAACACTAGCCGTGGAACCAAGTCAT
CCTGAACTTTATCAACATATCAGTTATACACCAATAAGCCTTGATGATTTATCGGTTACATTGAATTTGCCGGTGGATTT
GCTTTTAGTGCAGTTGTTAGATTTGGAGTTACAAGATTTAATCGTCAATGAGAATGGACTCTATAAGCGGATAGCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (70-277)

• DprA winged helix domain (DprA_WH) (311-363)

3D structure

• AlphaFold DB: A0A7M1NZQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	71.314	100	0.715
dprA	Glaesserella parasuis strain SC1401	57.267	92.473	0.53
dprA	Vibrio campbellii strain DS40M4	43.28	100	0.433
dprA	Vibrio cholerae strain A1552	42.818	99.194	0.425
dprA	Legionella pneumophila strain ERS1305867	40.27	99.462	0.401