Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INP98_RS00305 Genome accession   NZ_CP063112
Coordinates   56244..57467 (+) Length   407 a.a.
NCBI ID   WP_197570027.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M1C149_1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 51244..62467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP98_RS00280 (INP98_00280) - 51828..52622 (-) 795 WP_197570024.1 sulfite exporter TauE/SafE family protein -
  INP98_RS00285 (INP98_00285) rppH 52622..53215 (-) 594 WP_197570025.1 RNA pyrophosphohydrolase -
  INP98_RS00290 (INP98_00290) ampD 53700..54263 (-) 564 WP_197570026.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  INP98_RS00295 (INP98_00295) pilA 54406..54849 (+) 444 WP_005697917.1 prepilin peptidase-dependent pilin Machinery gene
  INP98_RS00300 (INP98_00300) pilB 54856..56235 (+) 1380 WP_197543655.1 GspE/PulE family protein Machinery gene
  INP98_RS00305 (INP98_00305) pilC 56244..57467 (+) 1224 WP_197570027.1 type II secretion system F family protein Machinery gene
  INP98_RS00310 (INP98_00310) pilD 57464..58141 (+) 678 WP_197570028.1 prepilin peptidase Machinery gene
  INP98_RS00315 (INP98_00315) coaE 58230..58850 (+) 621 WP_197543658.1 dephospho-CoA kinase -
  INP98_RS00320 (INP98_00320) yacG 58843..59049 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  INP98_RS00325 (INP98_00325) - 59046..59327 (+) 282 WP_197543659.1 GNAT family N-acetyltransferase -
  INP98_RS00330 (INP98_00330) rhlB 59418..60677 (+) 1260 WP_197570029.1 ATP-dependent RNA helicase RhlB -
  INP98_RS00335 (INP98_00335) mreD 60719..61207 (-) 489 WP_049364929.1 rod shape-determining protein MreD -
  INP98_RS00340 (INP98_00340) mreC 61207..62271 (-) 1065 WP_049369504.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46256.91 Da        Isoelectric Point: 9.7422

>NTDB_id=492937 INP98_RS00305 WP_197570027.1 56244..57467(+) (pilC) [Haemophilus parainfluenzae strain M1C149_1]
MVKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFLLIAKGFNHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLGALIELIESGISFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLALQRKLQ
KIMLYPVMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQHHFIALMIVCIFALFMLKMALKHSLW
LNQKKNALISRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQTQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=492937 INP98_RS00305 WP_197570027.1 56244..57467(+) (pilC) [Haemophilus parainfluenzae strain M1C149_1]
ATGGTAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGTCTTGTTGCTCAATC
TAAACAAGCCGCACAATTTCTGTTAATTGCAAAAGGTTTTAACCACATTCGCTTACAACAAGATTGGCAACTTAATCAGA
AACCTAAAAATGCTGAAATCAGTGCTTTATTAAATCAGCTAGCTACTCTGCTCAGCTCTGCCATTCCATTAAAAAATGCA
TTGCACATTTTGCAAGATAACTGCACGCAATTGGGATTGCATCAGTGGCTTGGCGCCTTAATTGAATTAATTGAAAGTGG
CATTTCGTTTTCACAAAGCTTGGAAATACAAGGAAAGTATTTAAATTTTCAAGAAATTCAACTTATTCAAGTGGGAGAGA
TGACAGGAAAACTGGCGGAGGTATGCACTAAAATCGCAGAACGTCGAACGCAATCATTAGCGCTTCAACGCAAATTACAA
AAAATTATGCTTTATCCTGTCATGGTATTAGGTATTTCGCTTTCACTTACGTTAATTTTATTACTCTTCGTTGTACCTCA
ATTTGCTGAAATGTATGGTGAAAACTCCGCTGAACTGCCTACATTAACTGCTGTGTTATTAGCCATGTCTCAATTCCTAC
AACATCATTTTATCGCCTTGATGATTGTCTGCATTTTCGCTCTTTTTATGCTAAAGATGGCACTAAAACATTCTCTTTGG
CTGAATCAAAAAAAGAATGCGCTGATTAGTCGCATGCCAATTTGGGGCAATATCATTTGCCTTTCTCGTTTAATCAGTTT
TAGCCATAATCTGCAATTAATGCTTCAATCCGGTGTAGCCTTAACGCCTGCGTTAAATAGTTTTCTTCCCAAACAGCAAA
CCTGGCAAACACAACGTACTTTAAAAGGCGATATCCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGCGTCAGTAGCCATCTTTTCCCGATGGAAGCGCAGCAAATGCTACAAATTGGCGAAAAAAG
TGGAAAACTTGCGTTGATGTTGCGCCATATTGCTGACAACTATCAAGAAAAGCTTAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCATTAATGATGCTCATTATTGGTAGTTTAATTGGTATCATAATGATGGGGATGTATCTGCCAATTTTT
AATATGGGTTCGGTAATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.802

99.263

0.693
  pilC Haemophilus influenzae 86-028NP

69.059

99.263

0.685
  pilC Glaesserella parasuis strain SC1401

39.9

98.526

0.393