Detailed information NTG0492920

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: INP99_RS03720
• Genome accession: NZ_CP063111
• Coordinates: 761042..762424 (+)
• Length: 460 a.a.
• NCBI ID: WP_197542725.1
• Uniprot ID: -
• Organism: Haemophilus parainfluenzae strain M1C152_1
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 756042..767424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP99_RS03695 (INP99_03690)	-	756059..758671 (-)	2613	WP_054420354.1	penicillin-binding protein 1A	-
INP99_RS03700 (INP99_03695)	-	758771..759613 (+)	843	WP_197542722.1	competence protein ComA	-
INP99_RS03705 (INP99_03700)	-	759606..760118 (+)	513	WP_197542723.1	competence protein ComB	-
INP99_RS03710 (INP99_03705)	-	760115..760657 (+)	543	WP_197542724.1	competence protein ComC	-
INP99_RS03715 (INP99_03710)	-	760657..761040 (+)	384	WP_070582959.1	pilus assembly protein PilP	-
INP99_RS03720 (INP99_03715)	comE	761042..762424 (+)	1383	WP_197542725.1	type IV pilus secretin PilQ	Machinery gene
INP99_RS03725 (INP99_03720)	-	762444..763133 (+)	690	WP_197542726.1	ComF family protein	-
INP99_RS03730 (INP99_03725)	nfuA	763249..763833 (+)	585	WP_014064659.1	Fe-S biogenesis protein NfuA	-
INP99_RS03735 (INP99_03730)	comM	763877..765406 (-)	1530	WP_197542727.1	YifB family Mg chelatase-like AAA ATPase	Machinery gene
INP99_RS03740 (INP99_03735)	yihA	765536..766150 (-)	615	WP_065243638.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
INP99_RS03745 (INP99_03740)	-	766264..767133 (+)	870	WP_197542728.1	VirK/YbjX family protein	-

Sequence

Protein

• Length: 460 a.a.
• Molecular weight: 51115.74 Da
• Isoelectric Point: 7.2239

>NTDB_id=492920 INP99_RS03720 WP_197542725.1 761042..762424(+) (comE) [Haemophilus parainfluenzae strain M1C152_1]
MIKQKIKTKCGQFLMCFLILWTTYSAAENRVFSLRLKQAPMVATLQQLALEQNANLMIDDELEGTLSLQLDNVDFDRLLR
SVAKIKGLSFYQENDIYYLGKLSQHEQYAEKMTEPMAISGESLSSETPLVSTTVKLHFAKASDVMKSLTTGSGSLLSPSG
TITFDDRSNVLLIQDDARSVKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTEAAHRVSGSLDANGFS
HISNNLNVNFATTVTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDT
QSVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGNRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKGV
DKVPLLGDIPGIKRLFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQVEKVKK

Nucleotide

• Length: 1383 bp

>NTDB_id=492920 INP99_RS03720 WP_197542725.1 761042..762424(+) (comE) [Haemophilus parainfluenzae strain M1C152_1]
ATGATAAAGCAGAAAATAAAAACAAAGTGCGGTCAGTTTTTAATGTGTTTTTTGATCCTATGGACAACTTACTCAGCGGC
AGAGAATCGCGTATTTTCACTTCGCTTAAAACAAGCTCCCATGGTGGCGACACTCCAGCAACTTGCTCTTGAGCAAAATG
CCAATTTAATGATTGATGATGAGCTAGAAGGAACGCTTTCATTGCAATTAGATAACGTAGATTTTGATCGTTTATTGCGT
TCTGTGGCAAAAATCAAAGGGCTCTCTTTTTATCAAGAAAATGATATTTATTATTTGGGTAAGCTTTCTCAACATGAACA
ATATGCAGAGAAAATGACAGAACCTATGGCAATTAGCGGAGAAAGTTTATCTAGTGAAACGCCACTTGTGAGTACAACGG
TTAAACTGCATTTTGCCAAGGCCTCTGATGTGATGAAATCTTTAACAACAGGGAGCGGTTCTTTGCTTTCACCTAGCGGC
ACAATTACATTTGATGATCGAAGCAATGTGTTACTGATTCAGGATGATGCTCGTTCTGTCAAAAATATCAAAAAATTGAT
TGCAGAGCTGGATAAACCCATTGAGCAAATCGTGATTGAAGCACGTATTGTGACGATTACAGATGAAAGCCTAAAAGAAT
TAGGTGTGCGTTGGGGTATTTTTAATCCGACTGAGGCTGCCCATCGAGTGAGTGGCAGTCTAGATGCGAATGGTTTTAGT
CATATCAGTAATAATTTAAACGTGAATTTTGCGACAACGGTCACGCCGGCTGGCTCATTGGCTCTTCAAGTCGCTAAAAT
TAATGGCCGATTATTAGACTTAGAATTGACCGCACTTGAACGTGAAAATAACGTAGAAATTATTGCAAGCCCTCGCTTAC
TTACGACCAACAAGAAAAGTGCAAGCATCAAACAAGGGACAGAAATTCCTTATGTGGTGACGAATGGGAAAAATGATACA
CAGTCAGTAGAGTTTCGCGAGGCTGTCTTAGGATTGGAAGTCACGCCGCATATTTCGAAGGATAATAATATCTTATTGGA
TTTATTAGTCAGTCAAAATTCTCCGGGAAATCGCGTGGCTTATGGGCAAAATGAAGTCGTATCCATTGATAAACAAGAAA
TTAATACGCAAGTGTTTGCCAAAGATGGGGAAACGATTGTATTGGGCGGCGTATTTCACGATACGATCACGAAAGGTGTC
GATAAAGTGCCATTATTGGGCGATATTCCAGGTATTAAGCGCTTATTCAGTAAGGAAAGTGAACGTCATCAAAAACGAGA
ACTCGTCATTTTTGTGACCCCTCATATTTTGAAACAAGGTGAAAGAATGGAAATGGCTAAGAAAGAAAAGCATTTTAAGC
AAGTTGAAAAAGTGAAAAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (278-438)

• Bacterial type II/III secretion system short domain (Secretin_N) (133-196)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	73.497	97.609	0.717
comE	Haemophilus influenzae 86-028NP	72.606	97.609	0.709
comE	Glaesserella parasuis strain SC1401	53.664	91.957	0.493
pilQ	Vibrio campbellii strain DS40M4	41.57	94.13	0.391
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	41.176	92.391	0.38
pilQ	Vibrio cholerae strain A1552	41.176	92.391	0.38