Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | ILQ36_RS02695 | Genome accession | NZ_CP062763 |
| Coordinates | 556872..557996 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228544.1 | Uniprot ID | A0A9P2PX49 |
| Organism | Escherichia coli O157:H7 strain Z885 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 535843..557996 | 556872..557996 | within | 0 |
Gene organization within MGE regions
Location: 535843..557996
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ILQ36_RS02505 (ILQ36_02505) | bfr | 535843..536319 (+) | 477 | WP_000675516.1 | bacterioferritin | - |
| ILQ36_RS02510 (ILQ36_02510) | - | 536316..536783 (-) | 468 | WP_000381746.1 | A24 family peptidase | - |
| ILQ36_RS02515 (ILQ36_02515) | rpsJ | 537162..537473 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| ILQ36_RS02520 (ILQ36_02520) | rplC | 537506..538135 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| ILQ36_RS02525 (ILQ36_02525) | rplD | 538146..538751 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| ILQ36_RS02530 (ILQ36_02530) | rplW | 538748..539050 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| ILQ36_RS02535 (ILQ36_02535) | rplB | 539068..539889 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| ILQ36_RS02540 (ILQ36_02540) | rpsS | 539906..540184 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| ILQ36_RS02545 (ILQ36_02545) | rplV | 540199..540531 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| ILQ36_RS02550 (ILQ36_02550) | rpsC | 540549..541250 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| ILQ36_RS02555 (ILQ36_02555) | rplP | 541263..541673 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| ILQ36_RS02560 (ILQ36_02560) | rpmC | 541673..541864 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| ILQ36_RS02565 (ILQ36_02565) | rpsQ | 541864..542118 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| ILQ36_RS02570 (ILQ36_02570) | rplN | 542283..542654 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| ILQ36_RS02575 (ILQ36_02575) | rplX | 542665..542979 (+) | 315 | WP_000729185.1 | 50S ribosomal protein L24 | - |
| ILQ36_RS02580 (ILQ36_02580) | rplE | 542994..543533 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| ILQ36_RS02585 (ILQ36_02585) | rpsN | 543548..543853 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| ILQ36_RS02590 (ILQ36_02590) | rpsH | 543887..544279 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| ILQ36_RS02595 (ILQ36_02595) | rplF | 544292..544825 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| ILQ36_RS02600 (ILQ36_02600) | rplR | 544835..545188 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| ILQ36_RS02605 (ILQ36_02605) | rpsE | 545203..545706 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| ILQ36_RS02610 (ILQ36_02610) | rpmD | 545710..545889 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| ILQ36_RS02615 (ILQ36_02615) | rplO | 545893..546327 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| ILQ36_RS02620 (ILQ36_02620) | secY | 546335..547666 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| ILQ36_RS02625 (ILQ36_02625) | rpmJ | 547698..547814 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| ILQ36_RS02630 (ILQ36_02630) | rpsM | 547961..548317 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| ILQ36_RS02635 (ILQ36_02635) | rpsK | 548334..548723 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| ILQ36_RS02640 (ILQ36_02640) | rpsD | 548757..549377 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| ILQ36_RS02645 (ILQ36_02645) | rpoA | 549403..550392 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| ILQ36_RS02650 (ILQ36_02650) | rplQ | 550433..550816 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| ILQ36_RS02655 (ILQ36_02655) | yhdN | 550923..551291 (+) | 369 | WP_000266488.1 | DUF1992 domain-containing protein | - |
| ILQ36_RS02660 (ILQ36_02660) | zntR | 551302..551727 (+) | 426 | WP_000285607.1 | Zn(2+)-responsive transcriptional regulator | - |
| ILQ36_RS02665 (ILQ36_02665) | arfA | 551783..552001 (+) | 219 | WP_000092696.1 | alternative ribosome-rescue factor ArfA | - |
| ILQ36_RS02670 (ILQ36_02670) | mscL | 551998..552408 (-) | 411 | WP_000022442.1 | large-conductance mechanosensitive channel protein MscL | - |
| ILQ36_RS02675 (ILQ36_02675) | trkA | 552538..553914 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| ILQ36_RS02680 (ILQ36_02680) | rsmB | 553936..555225 (-) | 1290 | WP_001301795.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| ILQ36_RS02685 (ILQ36_02685) | fmt | 555271..556218 (-) | 948 | WP_000004459.1 | methionyl-tRNA formyltransferase | - |
| ILQ36_RS02690 (ILQ36_02690) | def | 556233..556742 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| ILQ36_RS02695 (ILQ36_02695) | dprA | 556872..557996 (+) | 1125 | WP_000228544.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 41005.96 Da Isoelectric Point: 6.2655
>NTDB_id=491176 ILQ36_RS02695 WP_000228544.1 556872..557996(+) (dprA) [Escherichia coli O157:H7 strain Z885]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=491176 ILQ36_RS02695 WP_000228544.1 556872..557996(+) (dprA) [Escherichia coli O157:H7 strain Z885]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Glaesserella parasuis strain SC1401 |
45.401 |
90.107 |
0.409 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.545 |
88.235 |
0.393 |