Detailed information NTG0049116

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: TTJL18_RS03320
• Genome accession: NC_017587
• Coordinates: 585431..587698 (-)
• Length: 755 a.a.
• NCBI ID: WP_014629292.1
• Uniprot ID: H9ZQG0
• Organism: Thermus thermophilus JL-18
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 580431..592698

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTJL18_RS03290 (TtJL18_0659)	-	580441..580794 (+)	354	WP_014629288.1	DUF4870 domain-containing protein	-
TTJL18_RS03295 (TtJL18_0660)	-	580772..581149 (-)	378	WP_011173441.1	4'-phosphopantetheinyl transferase superfamily protein	-
TTJL18_RS03300 (TtJL18_0661)	rsmF	581202..582572 (+)	1371	WP_014629289.1	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	-
TTJL18_RS03305 (TtJL18_0662)	-	582618..583664 (-)	1047	WP_011228641.1	3-dehydroquinate synthase family protein	-
TTJL18_RS03310 (TtJL18_0663)	-	583642..584196 (-)	555	WP_014629290.1	shikimate kinase	-
TTJL18_RS03315 (TtJL18_0664)	aroC	584221..585372 (-)	1152	WP_041444488.1	chorismate synthase	-
TTJL18_RS03320 (TtJL18_0665)	pilQ	585431..587698 (-)	2268	WP_014629292.1	secretin N-terminal domain-containing protein	Machinery gene
TTJL18_RS03325 (TtJL18_0666)	pilW	587695..588543 (-)	849	WP_014629293.1	hypothetical protein	Machinery gene
TTJL18_RS03330 (TtJL18_0667)	pilO	588540..589121 (-)	582	WP_014629294.1	type 4a pilus biogenesis protein PilO	Machinery gene
TTJL18_RS03335 (TtJL18_0668)	pilN	589111..589734 (-)	624	WP_014629295.1	competence protein	Machinery gene
TTJL18_RS03340 (TtJL18_0669)	pilM	589727..590860 (-)	1134	WP_014629296.1	type IV pilus assembly protein PilM	Machinery gene
TTJL18_RS03345 (TtJL18_0670)	-	590990..591994 (-)	1005	WP_014629297.1	homoisocitrate dehydrogenase	-
TTJL18_RS03350 (TtJL18_0671)	-	592049..592540 (-)	492	WP_011173430.1	DUF5317 domain-containing protein	-

Sequence

Protein

• Length: 755 a.a.
• Molecular weight: 82657.61 Da
• Isoelectric Point: 5.1448

>NTDB_id=49116 TTJL18_RS03320 WP_014629292.1 585431..587698(-) (pilQ) [Thermus thermophilus JL-18]
MKSAWIRAAVIALAGLGAFALAGSFPEEPRFQAPVNLKVSESQVKAGQTLPLDVVLEALARSVGLQPLIYRAYDTSGDPA
KAEPPLPNVKLDFQGKPFREVWDLLFATYGNQYSLDYLFLPPDVVVVAPTQVITALVDAPSRTGAMERRPYIVGIPEIAY
KRTETDAQGQPRTVVNIEGAKAWVQNDLLPFLSREAAGLNVNWIVVEEGGRLKAVLSVLATPEQHARFSDILQRAGIDFR
PLPALAQPKPRVEKTYTLTYATFPELLAFLQSRLPEAQISVVPTNPQRAIVLATEEDHARLSELLKTADVPKTVRRVYAL
QNLTFREAQERLKPLLEKDLKGARLESLPGNPKALLLEAPEAEHALFAEILKALDVPPQTPQAPQEATLRRLYPLRYANA
EQVAPFLAREVPGIVVQTVPGQPILSVRGTERQLAEVETLLAQIDRAPEQGPPVFQRAYQLSNAKASDLARVLQEALQAR
QTQAQGQGQAQPRQATVVADERTNTLIVTGTQEDLALVEGLIPKLDQPVPQVSLRVRIQEVQSNLTRSLGLKWNSIAGGN
VAASILDSGLSLIFDSTRSLAALNIMATLDALQQQGLSRALRDVNQTVLNNQTARLQSGETFFIRRVVNDQVERVPFDVG
LIVEVTPQITADGQILLNIKAEVSGNVQRNPVDGDVDRFTKQVVTTTLRVKDGETVVLGGLTSQESNQSQQGVPLLMDIP
LIGELFKQRTNERTDKELLVVITADILEETASANP

Nucleotide

• Length: 2268 bp

>NTDB_id=49116 TTJL18_RS03320 WP_014629292.1 585431..587698(-) (pilQ) [Thermus thermophilus JL-18]
ATGAAGAGCGCGTGGATCCGTGCGGCCGTGATCGCCCTCGCAGGGCTAGGGGCTTTTGCCCTTGCGGGGAGCTTTCCCGA
GGAGCCCCGCTTCCAGGCCCCGGTGAACCTCAAGGTCTCGGAATCCCAGGTCAAGGCGGGCCAGACCCTGCCCCTGGACG
TGGTCCTCGAGGCCCTGGCAAGGAGCGTGGGGCTCCAGCCCCTCATCTACCGGGCCTACGATACAAGCGGGGACCCCGCC
AAGGCAGAGCCCCCCCTCCCCAACGTCAAGCTGGACTTCCAGGGCAAGCCCTTCCGGGAGGTCTGGGACCTCCTCTTCGC
CACCTACGGCAACCAGTACAGCCTGGACTACCTCTTCCTGCCCCCCGACGTGGTGGTGGTGGCCCCCACCCAGGTGATCA
CCGCCCTGGTGGACGCCCCGAGCCGCACGGGGGCCATGGAGCGGAGGCCCTACATCGTGGGCATCCCCGAGATCGCCTAC
AAGCGCACGGAGACGGACGCCCAGGGCCAGCCCCGCACGGTCGTCAACATTGAGGGCGCCAAGGCCTGGGTCCAGAACGA
CCTCCTCCCCTTCCTCTCCCGGGAGGCCGCGGGACTCAACGTGAACTGGATCGTGGTGGAGGAGGGCGGGAGGCTCAAGG
CCGTCCTCTCCGTTCTCGCCACCCCCGAGCAACACGCCCGCTTCTCCGACATCCTGCAACGGGCCGGGATTGACTTCCGC
CCCCTCCCCGCCCTGGCCCAGCCCAAGCCCCGGGTGGAGAAGACCTACACCCTCACCTACGCCACCTTCCCCGAACTCCT
CGCCTTCCTCCAGTCCCGCCTCCCCGAGGCCCAGATCAGCGTGGTTCCCACCAACCCCCAAAGGGCCATCGTCCTCGCCA
CCGAGGAGGACCACGCCCGCTTGAGCGAGCTTCTAAAGACGGCCGACGTCCCCAAGACCGTCCGCCGGGTCTACGCCCTG
CAGAACCTCACCTTCAGGGAGGCCCAGGAGCGCCTAAAGCCCCTCCTGGAGAAGGACCTCAAGGGGGCCCGCCTGGAGAG
CCTCCCCGGCAACCCCAAGGCCCTCCTCCTCGAGGCTCCCGAGGCGGAGCACGCCCTCTTCGCCGAGATCCTAAAAGCCC
TGGACGTCCCTCCCCAGACCCCTCAGGCTCCCCAGGAGGCCACCTTGCGCCGCCTTTACCCCTTGCGCTACGCCAACGCC
GAGCAGGTGGCCCCCTTCCTCGCCCGGGAGGTGCCGGGCATCGTGGTGCAGACCGTGCCGGGACAACCCATCCTCTCCGT
GCGGGGCACGGAGAGGCAACTGGCCGAGGTGGAAACCCTCCTCGCCCAGATTGACCGGGCCCCCGAGCAGGGCCCTCCCG
TGTTCCAGCGGGCCTACCAGCTCTCCAACGCCAAGGCCTCCGACCTGGCCAGGGTGCTGCAAGAAGCCCTCCAGGCCCGT
CAGACCCAAGCCCAAGGCCAAGGCCAGGCGCAACCCCGCCAGGCCACGGTGGTGGCGGACGAGCGCACCAACACCCTCAT
CGTCACCGGCACCCAGGAGGACCTCGCCCTGGTGGAGGGCCTCATCCCCAAGCTGGACCAGCCCGTTCCCCAGGTTTCCT
TGCGGGTGCGCATCCAGGAGGTCCAGTCCAACCTGACCCGTAGCCTCGGCCTCAAGTGGAACAGCATCGCCGGCGGCAAC
GTGGCGGCCAGCATCCTGGACTCGGGCCTTTCCCTCATCTTTGACTCCACGCGAAGCCTCGCCGCCCTCAACATCATGGC
CACCCTGGACGCCCTGCAGCAACAGGGCCTCTCCCGGGCCCTCCGGGACGTGAACCAGACCGTCCTCAACAACCAGACCG
CCCGCCTGCAGTCCGGCGAGACCTTCTTCATCCGGCGGGTGGTGAACGACCAGGTGGAACGGGTCCCCTTTGACGTGGGG
CTCATCGTGGAGGTCACGCCCCAGATCACCGCCGACGGCCAGATCCTCCTCAACATCAAGGCCGAGGTCTCGGGGAACGT
CCAGCGCAACCCCGTGGACGGGGACGTGGACCGCTTCACCAAGCAGGTGGTGACCACCACCCTCAGGGTCAAAGACGGGG
AGACCGTGGTCCTTGGGGGCCTCACCTCCCAGGAGTCCAACCAGAGCCAGCAGGGGGTGCCCCTCCTCATGGACATCCCC
CTGATCGGGGAACTTTTCAAGCAGCGGACGAACGAGCGCACCGACAAGGAGCTTTTGGTGGTGATCACCGCCGACATCCT
CGAGGAGACGGCCTCGGCGAACCCCTAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (591-747)

• Bacterial type II/III secretion system short domain (Secretin_N) (391-450)

• Bacterial type II/III secretion system short domain (Secretin_N) (457-531)

3D structure

• AlphaFold DB: H9ZQG0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Thermus thermophilus HB27	95.641	100	0.959