Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU76_RS01045 Genome accession   NZ_CP074028
Coordinates   206082..206738 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain PK13     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 201082..211738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU76_RS01015 (KFU76_00990) dcyD 201962..202948 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU76_RS01020 (KFU76_00995) tcyL 202963..203631 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU76_RS01025 (KFU76_01000) tcyN 203628..204380 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU76_RS01030 (KFU76_01005) sdiA 204610..205332 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  KFU76_RS01035 (KFU76_01010) yecF 205399..205623 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU76_RS01040 (KFU76_01015) yecU 205610..205786 (-) 177 WP_000590347.1 protein YecU -
  KFU76_RS23410 - 205869..205940 (-) 72 Protein_202 transcriptional regulator -
  KFU76_RS01045 (KFU76_01020) letA 206082..206738 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU76_RS01050 (KFU76_01025) uvrC 206735..208567 (+) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  KFU76_RS01055 (KFU76_01030) pgsA 208624..209172 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU76_RS01075 (KFU76_01050) - 209866..210606 (-) 741 WP_106661694.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=490098 KFU76_RS01045 WP_000611335.1 206082..206738(+) (letA) [Escherichia coli strain PK13]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=490098 KFU76_RS01045 WP_000611335.1 206082..206738(+) (letA) [Escherichia coli strain PK13]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486