Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   STH8232_RS02005 Genome accession   NC_017581
Coordinates   367996..368586 (+) Length   196 a.a.
NCBI ID   WP_002949732.1    Uniprot ID   Q5M5U4
Organism   Streptococcus thermophilus JIM 8232     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 362996..373586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS01975 (STH8232_0449) - 363375..363968 (+) 594 Protein_336 cation transporting ATPase C-terminal domain-containing protein -
  STH8232_RS01980 (STH8232_0450) - 364272..365366 (+) 1095 WP_002946733.1 cystathionine gamma-synthase -
  STH8232_RS01985 (STH8232_0451) - 365377..366540 (+) 1164 WP_011680761.1 MalY/PatB family protein -
  STH8232_RS01990 (STH8232_0452) - 366616..366783 (+) 168 WP_014621172.1 hypothetical protein -
  STH8232_RS01995 - 366824..367099 (+) 276 WP_011680763.1 hypothetical protein -
  STH8232_RS02000 (STH8232_0455) upp 367229..367858 (+) 630 WP_002946740.1 uracil phosphoribosyltransferase -
  STH8232_RS02005 (STH8232_0456) clpP 367996..368586 (+) 591 WP_002949732.1 ATP-dependent Clp protease proteolytic subunit Regulator
  STH8232_RS02010 (STH8232_0457) - 368673..369122 (+) 450 WP_014621174.1 YlbF family regulator -
  STH8232_RS02015 (STH8232_0458) - 369115..369396 (+) 282 WP_014621175.1 DUF2129 domain-containing protein -
  STH8232_RS02020 (STH8232_0459) - 369553..370728 (+) 1176 WP_014621176.1 ABC transporter substrate-binding protein -
  STH8232_RS02025 (STH8232_0460) - 370772..371656 (+) 885 WP_011225509.1 branched-chain amino acid ABC transporter permease -
  STH8232_RS02030 (STH8232_0461) - 371660..372610 (+) 951 WP_011225510.1 branched-chain amino acid ABC transporter permease -
  STH8232_RS02035 (STH8232_0462) - 372613..373377 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -

Sequence


Protein


Download         Length: 196 a.a.        Molecular weight: 21577.62 Da        Isoelectric Point: 4.4829

>NTDB_id=48980 STH8232_RS02005 WP_002949732.1 367996..368586(+) (clpP) [Streptococcus thermophilus JIM 8232]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPIEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
PIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=48980 STH8232_RS02005 WP_002949732.1 367996..368586(+) (clpP) [Streptococcus thermophilus JIM 8232]
ATGATTCCGGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTATAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTGGATGCTCAAGACA
ATACAAAAGATATCTATCTGTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGCCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGGATGGCAGCATCAATGGGTACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACTCAACAAA
CAGATATGGCTATCGCTGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
CCAATTGAAAAGGTTCATGTCGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains


Predicted by InterproScan.

(11-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5M5U4

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus thermophilus LMG 18311

100

100

1

  clpP Streptococcus thermophilus LMD-9

100

100

1

  clpP Streptococcus pneumoniae D39

92.821

99.49

0.923

  clpP Streptococcus pneumoniae R6

92.821

99.49

0.923

  clpP Streptococcus pneumoniae TIGR4

92.821

99.49

0.923

  clpP Streptococcus pneumoniae Rx1

92.821

99.49

0.923

  clpP Streptococcus pyogenes MGAS315

89.796

100

0.898

  clpP Streptococcus pyogenes JRS4

89.796

100

0.898

  clpP Streptococcus mutans UA159

87.755

100

0.878

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.245

100

0.872

  clpP Lactococcus lactis subsp. cremoris KW2

86.735

100

0.867

  clpP Bacillus subtilis subsp. subtilis str. 168

59.184

100

0.592

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.549

98.469

0.577


Multiple sequence alignment