Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I872_RS04150 Genome accession   NC_021175
Coordinates   860836..862200 (+) Length   454 a.a.
NCBI ID   WP_015604896.1    Uniprot ID   A0ABM5NJJ6
Organism   Streptococcus cristatus AS 1.3089     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 855836..867200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS04130 (I872_04130) - 856134..856454 (+) 321 WP_015604892.1 hypothetical protein -
  I872_RS04135 (I872_04135) - 856701..859244 (+) 2544 WP_015604893.1 M1 family metallopeptidase -
  I872_RS04140 (I872_04140) - 859629..860051 (+) 423 WP_041826796.1 hypothetical protein -
  I872_RS04145 (I872_04145) ciaR 860172..860846 (+) 675 WP_015604895.1 response regulator transcription factor Regulator
  I872_RS04150 (I872_04150) ciaH 860836..862200 (+) 1365 WP_015604896.1 sensor histidine kinase Regulator
  I872_RS04155 (I872_04155) - 862275..862661 (+) 387 WP_015604897.1 VOC family protein -
  I872_RS04160 (I872_04160) - 862750..864147 (+) 1398 WP_015604898.1 polysaccharide deacetylase family protein -
  I872_RS04165 (I872_04165) - 864229..865317 (-) 1089 WP_015604899.1 DEAD/DEAH box helicase -
  I872_RS04170 - 865310..866289 (-) 980 Protein_807 Gfo/Idh/MocA family protein -
  I872_RS04175 (I872_04180) udk 866394..867029 (+) 636 WP_005591973.1 uridine kinase -

Sequence

Protein


Download         Length: 454 a.a.        Molecular weight: 51629.04 Da        Isoelectric Point: 8.7586

>NTDB_id=48513 I872_RS04150 WP_015604896.1 860836..862200(+) (ciaH) [Streptococcus cristatus AS 1.3089]
MLNKLKKALYADDFSYFIRYFGVFTLIFSAMTLIIIQVMRSSLYTTVDDNLKSLSQNPAWVANLAYRTTGRQYQEPENKD
SEHEPAPDIKIEEPGRVNVSANTSAILLNDDYQNVSAKNGFLNFDAIKFNKRFLNQIKQIQLTNSYGQVESYRAYMFDID
PDDEIENVKYAVVMTSISQLEQTSEKHEKLIAIVMISFWGISLIASIYLARMSVKPLLDSMQKQKSFVENASHELRTPLA
VLQNRLESLFRKPEATIMESSESIASSLEEVRNMRLLTTNLLNLARRDDGIKPEYGEVTPDFFTTAFSNYAIIAEESDKV
FDFKNLVSKSITTDKVLLKQVMTILFDNAIKYTEEDGEIYFVASANDRSLTLRISDNGPGIAGDDKKKVFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVDALRGTISVKDNKPRGTIFEIKLPLKSDIRKRISKS

Nucleotide


Download         Length: 1365 bp        

>NTDB_id=48513 I872_RS04150 WP_015604896.1 860836..862200(+) (ciaH) [Streptococcus cristatus AS 1.3089]
ATGCTGAATAAACTCAAAAAAGCCTTATATGCGGATGATTTTTCTTATTTCATTCGCTATTTTGGTGTATTCACCCTGAT
TTTCTCGGCCATGACGCTCATTATTATCCAAGTCATGCGCTCCAGCCTTTACACGACCGTTGATGATAATCTCAAAAGTC
TCAGTCAAAATCCCGCCTGGGTAGCCAATCTAGCCTATCGGACGACGGGGCGGCAATACCAAGAGCCAGAGAATAAGGAT
TCAGAGCATGAGCCGGCTCCCGATATCAAGATTGAGGAGCCGGGTAGGGTCAATGTCAGTGCCAATACTTCAGCCATTCT
TTTGAATGATGATTATCAGAATGTATCAGCCAAGAATGGATTTTTAAACTTTGATGCGATTAAATTTAATAAACGATTTC
TTAATCAAATCAAGCAAATACAACTAACTAATAGCTATGGACAGGTCGAGAGTTATCGGGCTTATATGTTTGACATTGAT
CCAGATGATGAAATTGAAAATGTCAAATACGCGGTTGTTATGACCAGTATCAGCCAGCTGGAGCAGACTAGCGAAAAGCA
TGAAAAGCTAATTGCGATTGTCATGATTAGCTTCTGGGGTATTTCCTTGATTGCCAGTATCTATCTGGCGCGGATGAGTG
TCAAGCCTCTCTTGGACAGCATGCAAAAGCAGAAGTCCTTTGTTGAAAATGCTAGCCACGAATTGCGGACGCCTCTAGCT
GTGCTGCAAAATCGACTGGAATCTCTTTTCCGTAAGCCCGAGGCTACGATTATGGAGTCTAGTGAGAGTATCGCGTCCAG
TTTAGAGGAAGTGCGAAATATGCGTCTACTCACGACCAACTTACTCAATCTAGCAAGGCGAGATGACGGCATAAAGCCAG
AATACGGTGAAGTCACGCCAGACTTCTTCACGACAGCTTTTTCTAACTATGCTATTATCGCGGAGGAGAGCGATAAGGTC
TTTGATTTCAAAAATCTGGTTTCTAAATCAATCACGACAGATAAGGTCTTACTCAAGCAGGTCATGACCATCCTTTTTGA
TAATGCCATCAAATACACGGAAGAAGATGGAGAAATCTATTTCGTGGCCTCCGCCAATGATCGGAGCTTAACCTTGCGGA
TCTCTGACAATGGCCCAGGGATTGCGGGCGACGACAAGAAAAAAGTCTTCGATCGTTTTTATCGGGTGGACAAGGCTCGG
ACTCGGCAAAAGGGTGGTTTTGGACTGGGCCTATCCTTGGCGAAACAAATAGTAGACGCCCTGAGAGGGACCATCTCGGT
CAAAGACAACAAGCCACGTGGAACTATCTTTGAAATCAAACTACCCCTTAAGTCAGATATTAGAAAACGAATCAGTAAAA
GTTGA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-444)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

63.556

99.119

0.63
  ciaH Streptococcus pneumoniae D39

63.556

99.119

0.63
  ciaH Streptococcus pneumoniae R6

63.556

99.119

0.63
  ciaH Streptococcus pneumoniae TIGR4

63.556

99.119

0.63
  ciaH Streptococcus mutans UA159

52.608

97.137

0.511

Multiple sequence alignment