Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilM   Type   Machinery gene
Locus tag   IDM46_RS11185 Genome accession   NZ_CP061714
Coordinates   2389069..2390127 (-) Length   352 a.a.
NCBI ID   WP_182824784.1    Uniprot ID   A0A7X0UX43
Organism   Luteimonas sp. MC1825     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2360094..2407128 2389069..2390127 within 0


Gene organization within MGE regions


Location: 2360094..2407128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IDM46_RS11060 (IDM46_11060) - 2363390..2364199 (-) 810 WP_185115735.1 DsbC family protein -
  IDM46_RS11065 (IDM46_11065) xerD 2364314..2365261 (-) 948 WP_185115736.1 site-specific tyrosine recombinase XerD -
  IDM46_RS11070 (IDM46_11070) - 2365309..2365809 (+) 501 WP_182824834.1 RDD family protein -
  IDM46_RS11075 (IDM46_11075) - 2365815..2366444 (+) 630 WP_185115737.1 DsbA family oxidoreductase -
  IDM46_RS11080 (IDM46_11080) gap 2366515..2367519 (-) 1005 WP_185115738.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  IDM46_RS11085 (IDM46_11085) - 2367692..2368318 (+) 627 WP_182824828.1 OmpW family outer membrane protein -
  IDM46_RS11090 (IDM46_11090) - 2368360..2369262 (+) 903 WP_182824826.1 S1/P1 nuclease -
  IDM46_RS11095 (IDM46_11095) modA 2369356..2370147 (+) 792 WP_185115739.1 molybdate ABC transporter substrate-binding protein -
  IDM46_RS11100 (IDM46_11100) modB 2370168..2370872 (+) 705 WP_182824822.1 molybdate ABC transporter permease subunit -
  IDM46_RS11105 (IDM46_11105) - 2370898..2371518 (+) 621 WP_185115740.1 ATP-binding cassette domain-containing protein -
  IDM46_RS11110 (IDM46_11110) - 2371545..2372861 (-) 1317 WP_185115741.1 TonB family protein -
  IDM46_RS11115 (IDM46_11115) - 2372845..2373216 (-) 372 WP_185115742.1 BlaI/MecI/CopY family transcriptional regulator -
  IDM46_RS11120 (IDM46_11120) - 2373467..2374570 (-) 1104 WP_185115743.1 PLP-dependent cysteine synthase family protein -
  IDM46_RS11125 (IDM46_11125) tkt 2374598..2376586 (-) 1989 WP_182824812.1 transketolase -
  IDM46_RS11130 (IDM46_11130) - 2376682..2378010 (-) 1329 WP_185115744.1 dicarboxylate/amino acid:cation symporter -
  IDM46_RS11135 (IDM46_11135) - 2378072..2379736 (-) 1665 WP_223877962.1 BatD family protein -
  IDM46_RS11140 (IDM46_11140) - 2379741..2381591 (-) 1851 WP_185115745.1 VWA domain-containing protein -
  IDM46_RS11145 (IDM46_11145) - 2381588..2382553 (-) 966 WP_223878075.1 VWA domain-containing protein -
  IDM46_RS11150 (IDM46_11150) - 2382604..2383059 (-) 456 WP_185115747.1 DUF4381 domain-containing protein -
  IDM46_RS11155 (IDM46_11155) - 2383059..2384027 (-) 969 WP_223877963.1 DUF58 domain-containing protein -
  IDM46_RS11160 (IDM46_11160) - 2384024..2385016 (-) 993 WP_185115748.1 MoxR family ATPase -
  IDM46_RS11165 (IDM46_11165) pilQ 2385159..2387117 (-) 1959 WP_185115749.1 type IV pilus secretin PilQ -
  IDM46_RS11170 (IDM46_11170) - 2387132..2387671 (-) 540 WP_185115750.1 pilus assembly protein PilP -
  IDM46_RS11175 (IDM46_11175) pilO 2387673..2388347 (-) 675 WP_182824788.1 type 4a pilus biogenesis protein PilO -
  IDM46_RS11180 (IDM46_11180) - 2388344..2389069 (-) 726 WP_182824786.1 PilN domain-containing protein -
  IDM46_RS11185 (IDM46_11185) pilM 2389069..2390127 (-) 1059 WP_182824784.1 pilus assembly protein PilM Machinery gene
  IDM46_RS11190 (IDM46_11190) - 2390360..2392843 (+) 2484 WP_185115751.1 penicillin-binding protein 1A -
  IDM46_RS11195 (IDM46_11195) - 2392892..2393545 (+) 654 WP_185115752.1 hypothetical protein -
  IDM46_RS11200 (IDM46_11200) - 2393644..2394909 (-) 1266 WP_223878076.1 citrate synthase -
  IDM46_RS11205 (IDM46_11205) - 2395164..2395406 (-) 243 WP_182824775.1 type B 50S ribosomal protein L31 -
  IDM46_RS11210 (IDM46_11210) - 2395477..2396415 (-) 939 WP_185115754.1 nucleoside hydrolase -
  IDM46_RS11215 (IDM46_11215) recG 2396447..2398567 (-) 2121 WP_223877964.1 ATP-dependent DNA helicase RecG -
  IDM46_RS11220 (IDM46_11220) - 2398572..2398955 (-) 384 WP_185116087.1 RidA family protein -
  IDM46_RS11225 (IDM46_11225) - 2399024..2401192 (-) 2169 WP_182824769.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -
  IDM46_RS11230 (IDM46_11230) rpoZ 2401327..2401629 (-) 303 WP_182824766.1 DNA-directed RNA polymerase subunit omega -
  IDM46_RS11235 (IDM46_11235) gmk 2401759..2402397 (-) 639 WP_185115755.1 guanylate kinase -
  IDM46_RS11240 (IDM46_11240) - 2402390..2403250 (-) 861 WP_185115756.1 YicC/YloC family endoribonuclease -
  IDM46_RS11245 (IDM46_11245) rph 2403318..2404052 (+) 735 WP_185115757.1 ribonuclease PH -
  IDM46_RS11250 (IDM46_11250) rdgB 2404056..2404649 (+) 594 WP_185115758.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
  IDM46_RS11255 (IDM46_11255) hemW 2404646..2405803 (+) 1158 WP_185116088.1 radical SAM family heme chaperone HemW -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 37805.35 Da        Isoelectric Point: 4.4070

>NTDB_id=484350 IDM46_RS11185 WP_182824784.1 2389069..2390127(-) (pilM) [Luteimonas sp. MC1825]
MGLITKSQAPLVGVDISSTAVKLLQLSRSGDRYRVEHYAVEPLPPNAVVEKNIVEVEAVGEAIRRAMTRSGSKAKHAAAA
VAGSAVITKVIPMPADLDEDDLESQVELEAVNYIPYPIEEVNLDFEVLGAMPGNAEMVQVLLAASRSENVEMRASALELG
GLTARVMDVEAFAIENAFALLANTLNVPRDGIVALVDIGATMTTLNILRNGRSLYTREQVFGGKQLTDEVMRRYGLSYEE
AGLAKRQGGLPESYEIEVLEPFKEALVQQISRLLQFFYAGSEFNRVDQVVLAGGCASIGGVAEMVEEQLGVQTVIANPLA
QMTLGSRVQAHALAQDAPALMIACGLAMRSFD

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=484350 IDM46_RS11185 WP_182824784.1 2389069..2390127(-) (pilM) [Luteimonas sp. MC1825]
GTGGGGCTGATCACAAAAAGCCAGGCACCGCTGGTCGGGGTCGACATCAGTTCGACTGCGGTCAAGCTGTTGCAGCTGTC
GCGTTCGGGCGACCGATACCGGGTCGAGCACTACGCGGTTGAACCGCTGCCGCCCAATGCTGTCGTCGAGAAGAACATCG
TCGAGGTCGAGGCTGTCGGCGAAGCCATCCGCCGCGCCATGACGCGGTCCGGCAGCAAGGCGAAGCACGCCGCGGCCGCG
GTCGCCGGCTCGGCGGTGATCACCAAGGTGATCCCGATGCCGGCCGACCTCGACGAGGACGACCTCGAATCGCAGGTCGA
ACTCGAGGCGGTCAACTACATTCCGTATCCGATCGAGGAAGTGAACCTCGACTTCGAAGTGCTGGGTGCCATGCCAGGCA
ACGCCGAGATGGTGCAGGTGCTGCTGGCGGCGTCGCGTTCGGAGAACGTGGAGATGCGCGCGTCCGCGCTGGAGCTCGGC
GGCCTCACCGCCAGGGTCATGGACGTCGAGGCCTTCGCGATCGAGAACGCCTTCGCGCTGCTCGCCAATACGCTCAACGT
GCCGCGCGACGGCATCGTGGCGCTGGTCGACATCGGCGCCACCATGACCACGCTCAACATCCTCCGCAACGGCCGCAGTC
TCTACACGCGCGAGCAGGTCTTCGGCGGCAAGCAGTTGACCGACGAGGTCATGCGCCGCTACGGCCTGTCCTACGAGGAA
GCCGGCCTGGCCAAGCGCCAGGGCGGGCTGCCGGAAAGCTACGAGATCGAGGTGCTGGAGCCGTTCAAGGAAGCGCTGGT
CCAGCAGATCAGCCGCCTGCTGCAGTTCTTCTACGCCGGCAGCGAGTTCAACCGTGTCGACCAGGTGGTGCTGGCCGGTG
GCTGCGCCTCGATCGGCGGCGTGGCCGAGATGGTCGAGGAGCAGCTCGGCGTGCAGACCGTCATCGCCAACCCGCTGGCG
CAGATGACCCTGGGGTCCCGCGTCCAGGCGCATGCTCTCGCGCAGGATGCCCCGGCGCTGATGATCGCCTGCGGCCTGGC
CATGAGGAGCTTCGACTGA

Domains

Predicted by InterproScan.

Type IV pilus assembly protein PilM; (PilM_2)

(13-351)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X0UX43

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilM Acinetobacter baumannii D1279779

51.42

100

0.514
  comM Acinetobacter nosocomialis M2

51.136

100

0.511
  comM Acinetobacter baylyi ADP1

50

100

0.5
  pilM Legionella pneumophila strain ERS1305867

43.343

100

0.435