Detailed information NTG0482093

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: J7T78_RS07685
• Genome accession: NZ_CP072427
• Coordinates: 1493756..1495996 (-)
• Length: 746 a.a.
• NCBI ID: WP_014608613.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24750
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1488756..1500996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T78_RS07665 (J7T78_07615)	-	1489620..1490480 (-)	861	WP_138496494.1	methionyl aminopeptidase	-
J7T78_RS07670 (J7T78_07620)	spxR	1490524..1491804 (-)	1281	WP_138496492.1	CBS-HotDog domain-containing transcription factor SpxR	-
J7T78_RS07675 (J7T78_07625)	-	1491797..1492342 (-)	546	WP_138496490.1	GNAT family N-acetyltransferase	-
J7T78_RS07680 (J7T78_07630)	-	1492408..1493670 (-)	1263	WP_014608612.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7T78_RS07685 (J7T78_07635)	comEC/celB	1493756..1495996 (-)	2241	WP_014608613.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
J7T78_RS07690 (J7T78_07640)	comEA	1495986..1496681 (-)	696	WP_014608614.1	helix-hairpin-helix domain-containing protein	Machinery gene
J7T78_RS07695 (J7T78_07645)	-	1496789..1497544 (-)	756	WP_002948862.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
J7T78_RS07700	-	1497744..1498277 (+)	534	WP_014608615.1	polysaccharide deacetylase family protein	-
J7T78_RS07705	-	1498374..1498535 (+)	162	WP_224102936.1	hypothetical protein	-
J7T78_RS07710 (J7T78_07655)	-	1498585..1499349 (+)	765	WP_014608617.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
J7T78_RS07715 (J7T78_07660)	-	1499353..1499622 (+)	270	WP_011226404.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84879.77 Da
• Isoelectric Point: 9.8901

>NTDB_id=482093 J7T78_RS07685 WP_014608613.1 1493756..1495996(-) (comEC/celB) [Streptococcus thermophilus strain S24750]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLVICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TPAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDREQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHAVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKDSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=482093 J7T78_RS07685 WP_014608613.1 1493756..1495996(-) (comEC/celB) [Streptococcus thermophilus strain S24750]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGGTGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAGGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGCCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTACTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGACTCTTCATCAGAAGCTTTTTTGGACCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.721	100	0.477
comEC/celB	Streptococcus mitis SK321	46.854	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	45.917	100	0.46
comEC/celB	Streptococcus pneumoniae Rx1	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae D39	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae R6	45.649	100	0.457
comEC	Lactococcus lactis subsp. cremoris KW2	44.966	97.185	0.437