Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   D39N_RS09540 Genome accession   NZ_CP061208
Coordinates   1880138..1880845 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain D39_P0     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1875138..1885845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D39N_RS09520 (D39N_01912) argR 1876425..1876871 (-) 447 WP_001231472.1 arginine repressor -
  D39N_RS09525 (D39N_01913) argS 1877019..1878710 (+) 1692 WP_001092739.1 arginine--tRNA ligase -
  D39N_RS09530 (D39N_01914) - 1879025..1879571 (-) 547 Protein_1866 transposase -
  D39N_RS09535 (D39N_01915) - 1879578..1880054 (+) 477 WP_000356601.1 cupin domain-containing protein -
  D39N_RS09540 (D39N_01916) vicR 1880138..1880845 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  D39N_RS09545 (D39N_01917) - 1880846..1882177 (+) 1332 WP_000833273.1 ATP-binding protein -
  D39N_RS09550 (D39N_01918) - 1882344..1883219 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  D39N_RS09555 (D39N_01919) pstC 1883337..1884200 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  D39N_RS09560 (D39N_01920) pstA 1884193..1885008 (+) 816 WP_000049767.1 phosphate ABC transporter permease PstA -
  D39N_RS09565 (D39N_01921) pstB 1885010..1885762 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=481435 D39N_RS09540 WP_000166475.1 1880138..1880845(+) (vicR) [Streptococcus pneumoniae strain D39_P0]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=481435 D39N_RS09540 WP_000166475.1 1880138..1880845(+) (vicR) [Streptococcus pneumoniae strain D39_P0]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396