Detailed information NTG0481394

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: D39N_RS04360
• Genome accession: NZ_CP061208
• Coordinates: 879612..880565 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain D39_P0
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 874612..885565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D39N_RS04335	rpmG	875355..875504 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
D39N_RS04340 (D39N_00877)	secG	875544..875777 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
D39N_RS04345 (D39N_00878)	rnr	875879..878233 (+)	2355	WP_000654897.1	ribonuclease R	-
D39N_RS04350 (D39N_00879)	smpB	878196..878663 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
D39N_RS04355 (D39N_00880)	tehB	878679..879539 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
D39N_RS04360 (D39N_00881)	coiA	879612..880565 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
D39N_RS04365 (D39N_00882)	pepF	880584..882386 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
D39N_RS04370 (D39N_00883)	-	882388..883101 (+)	714	WP_000230399.1	O-methyltransferase	-
D39N_RS04375 (D39N_00884)	prsA	883168..884109 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
D39N_RS04380 (D39N_00885)	-	884228..884569 (-)	342	Protein_880	IS3 family transposase	-
D39N_RS04385	-	884981..885076 (+)	96	Protein_881	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=481394 D39N_RS04360 WP_000495911.1 879612..880565(+) (coiA) [Streptococcus pneumoniae strain D39_P0]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=481394 D39N_RS04360 WP_000495911.1 879612..880565(+) (coiA) [Streptococcus pneumoniae strain D39_P0]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435