Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   NMBH4476_RS00095 Genome accession   NC_017516
Coordinates   17190..17693 (-) Length   167 a.a.
NCBI ID   WP_014581605.1    Uniprot ID   -
Organism   Neisseria meningitidis H44/76     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 12190..22693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBH4476_RS00080 (NMBH4476_0016) gnd 12207..13655 (-) 1449 WP_002225759.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  NMBH4476_RS00090 (NMBH4476_0017) lpxC 15182..16105 (-) 924 WP_002216134.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  NMBH4476_RS13560 - 16097..16540 (+) 444 WP_141562916.1 hypothetical protein -
  NMBH4476_RS00095 (NMBH4476_0018) pilE 17190..17693 (-) 504 WP_014581605.1 pilin Machinery gene
  NMBH4476_RS00100 (NMBH4476_0019) - 18469..18894 (-) 426 Protein_18 pilin -
  NMBH4476_RS00105 (NMBH4476_0020) - 19219..19605 (-) 387 Protein_19 pilin -
  NMBH4476_RS00110 (NMBH4476_0021) - 19870..20259 (-) 390 Protein_20 pilin -
  NMBH4476_RS00115 (NMBH4476_0022) - 20784..21116 (-) 333 Protein_21 pilin -
  NMBH4476_RS00120 (NMBH4476_0023) - 21422..21844 (-) 423 Protein_22 pilin -
  NMBH4476_RS15280 - 22122..22433 (-) 312 Protein_23 pilin -

Sequence

Protein


Download         Length: 167 a.a.        Molecular weight: 17758.30 Da        Isoelectric Point: 9.3477

>NTDB_id=48034 NMBH4476_RS00095 WP_014581605.1 17190..17693(-) (pilE) [Neisseria meningitidis H44/76]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGEWPGNNSSAGVATSANIK
GKYVEKVEVKNGVVTATMLSTGVNKEIKGKKLSLWAKRQDGSVKWFCGQPVTRTDAKADTVAAAAKTADNINTKHLPSTC
RDASDAS

Nucleotide


Download         Length: 504 bp        

>NTDB_id=48034 NMBH4476_RS00095 WP_014581605.1 17190..17693(-) (pilE) [Neisseria meningitidis H44/76]
ATGAACACCCTTCAAAAAGGTTTTACCCTTATCGAGCTGATGATTGTGATTGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCTGCTTATCAAGACTACACAGCCCGCGCACAAGTTTCCGAAGCCATTCTTTTGGCTGAAGGTCAAAAATCAGCCG
TCACCGAGTATTACCTGAATCACGGCGAATGGCCCGGCAACAACAGTTCTGCCGGCGTGGCAACCTCCGCCAACATCAAA
GGCAAATATGTTGAGAAAGTTGAAGTCAAAAACGGCGTCGTTACCGCCACAATGCTTTCAACCGGCGTAAACAAAGAAAT
CAAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCA
CCGACGCCAAAGCCGACACCGTCGCCGCCGCCGCCAAGACCGCCGACAACATCAACACCAAGCACCTGCCGTCAACCTGC
CGCGACGCAAGTGATGCCAGCTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-161)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae MS11

82.143

100

0.826
  pilE Neisseria gonorrhoeae strain FA1090

82.036

100

0.82
  comP Acinetobacter baylyi ADP1

37.952

99.401

0.377
  pilA/pilA1 Eikenella corrodens VA1

36.628

100

0.377

Multiple sequence alignment